| Players | Clubs | Position | Total | Goals | A |  |
 |
 |
Start | Sub | CO | Off | Pen S | Pen SV | Pen M | Pen C | OG | More |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nick Marsman | FC Twente | Goalkeeper | 34 | 0 | 0 | 2 | 0 | 0 | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |
| Kamohelo Mokotjo | FC Twente | Midfielder | 33 | 1 | 2 | 0 | 0 | 0 | 32 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Enes Unal | FC Twente | Forward | 32 | 18 | 3 | 2 | 0 | 0 | 31 | 1 | 1 | 5 | 0 | 0 | 0 | 0 | 0 | |
| Hidde ter Avest | FC Twente | Defender | 31 | 1 | 0 | 5 | 1 | 0 | 31 | 2 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | |
| Mateusz Klich | FC Twente | Midfielder | 29 | 6 | 4 | 8 | 0 | 0 | 29 | 0 | 0 | 1 | 6 | 0 | 0 | 0 | 0 | |
| Stefan Thesker | FC Twente | Defender | 29 | 0 | 2 | 3 | 0 | 0 | 28 | 3 | 1 | 4 | 0 | 0 | 0 | 0 | 1 | |
| Bersant Celina | FC Twente | Midfielder | 27 | 5 | 4 | 1 | 0 | 1 | 26 | 2 | 1 | 10 | 0 | 0 | 0 | 0 | 0 | |
| Jeroen van der Lely | FC Twente | Defender | 27 | 0 | 0 | 3 | 0 | 0 | 25 | 9 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | |
| Peet Bijen | FC Twente | Midfielder | 26 | 0 | 1 | 4 | 0 | 0 | 23 | 10 | 3 | 1 | 0 | 0 | 0 | 0 | 2 | |
| Yaw Yeboah | FC Twente | Forward | 26 | 2 | 1 | 2 | 0 | 0 | 20 | 13 | 6 | 12 | 0 | 0 | 0 | 0 | 0 | |
| Fredrik Jensen | FC Twente | Midfielder | 24 | 4 | 2 | 0 | 0 | 0 | 17 | 12 | 7 | 14 | 0 | 0 | 0 | 0 | 0 | |
| Joachim Andersen | FC Twente | Defender | 22 | 2 | 0 | 3 | 1 | 0 | 21 | 8 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | |
| Dejan Trajkovski | FC Twente | Defender | 22 | 0 | 3 | 5 | 0 | 0 | 16 | 14 | 6 | 3 | 0 | 0 | 0 | 0 | 0 | |
| Chinedu Ede | FC Twente | Midfielder | 22 | 0 | 6 | 1 | 0 | 0 | 14 | 12 | 8 | 11 | 0 | 0 | 0 | 0 | 0 | |
| Dylan Seys | FC Twente | Midfielder | 17 | 1 | 0 | 2 | 0 | 0 | 8 | 16 | 9 | 7 | 0 | 0 | 0 | 0 | 0 | |
| Jari Oosterwijk | FC Twente | Forward | 12 | 2 | 0 | 0 | 0 | 0 | 3 | 17 | 9 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Jelle van der Heyden | FC Twente | Midfielder | 10 | 0 | 0 | 0 | 0 | 0 | 6 | 28 | 4 | 3 | 0 | 0 | 0 | 0 | 0 | |
| Dylan George | FC Twente | Midfielder | 8 | 1 | 0 | 0 | 0 | 0 | 2 | 16 | 6 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Jos Hooiveld | FC Twente | Defender | 7 | 0 | 0 | 1 | 0 | 0 | 1 | 12 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Oussama Assaidi | FC Twente | Forward | 5 | 1 | 0 | 0 | 0 | 0 | 3 | 3 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | |
| Tim Holscher | FC Twente | Midfielder | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 18 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Hakim Ziyech | FC Twente | Forward | 4 | 2 | 1 | 1 | 0 | 0 | 4 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Enis Bunjaki | FC Twente | Forward | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 12 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Giorgos Katsikas | FC Twente | Defender | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 16 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Torgeir Borven | FC Twente | Forward | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Brem Soumaoro | FC Twente | Midfielder | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Joel Drommel | FC Twente | Goalkeeper | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 30 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Kyle Ebecilio | FC Twente | Midfielder | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Nick Hengelman | FC Twente | Goalkeeper | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 21 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Pelle Boevink | FC Twente | Goalkeeper | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Sonny Stevens | FC Twente | Goalkeeper | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A = Assists,
CS = Clean sheets Full
Sub = Started as a sub,
CO = Came on,
Off = Taken off,
S = Scored,
M = Missed,
Total = Total appearances,
OG = Own goals.