| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Ledley King | 38 | 38 | - | - | - | 2 |
Paul Robinson | 36 | 36 | - | - | 1 | - |
Jermain Defoe | 35 | 28 | 7 | 7 | 10 | 13 |
Robbie Keane | 35 | 23 | 13 | 12 | 6 | 11 |
Frederic Kanoute | 32 | 22 | 10 | 10 | 8 | 7 |
Michael Carrick | 29 | 26 | 3 | 3 | 2 | - |
Erik Edman | 28 | 28 | 1 | - | 4 | 1 |
Noureddine Naybet | 27 | 27 | 1 | - | 5 | 1 |
Pedro Mendes | 24 | 22 | 2 | 2 | 4 | 1 |
Michael Brown | 24 | 20 | 9 | 4 | 6 | 1 |
Noe Pamarot | 23 | 23 | 3 | - | 4 | 1 |
Reto Ziegler | 23 | 12 | 15 | 11 | 8 | 1 |
Simon Davies | 21 | 17 | 4 | 4 | 3 | - |
Timothee Atouba | 18 | 15 | 4 | 3 | 7 | 1 |
Stephen Kelly | 17 | 13 | 5 | 4 | 1 | 2 |
Anthony Gardner | 17 | 8 | 16 | 9 | 1 | - |
Sean Davis | 15 | 11 | 5 | 4 | 4 | - |
Jamie Redknapp | 14 | 9 | 10 | 5 | 5 | - |
Andy Reid | 13 | 13 | - | - | 5 | 1 |
Hossam Mido | 9 | 4 | 6 | 5 | 4 | 2 |
Johnnie Jackson | 8 | 3 | 5 | 5 | 3 | - |
Rohan Ricketts | 6 | 5 | 1 | 1 | 4 | - |
Michael Dawson | 5 | 5 | - | - | - | - |
Dean Marney | 5 | 3 | 6 | 2 | 1 | 2 |
Goran Bunjevcevic | 3 | 2 | 8 | 1 | - | - |
Radek Cerny | 3 | 2 | 12 | 1 | - | - |
Philip Ifil | 2 | 2 | 2 | - | - | - |
Mark Yeates | 2 | - | 4 | 2 | - | - |
Mbulelo Mabizela | 1 | 1 | 1 | - | 1 | - |
Calum Davenport | 1 | - | 5 | 1 | - | - |
Gary Doherty | 1 | - | 1 | 1 | - | - |
Edson Silva Sousa | - | - | 4 | - | - | - |
Marton Fulop | - | - | 13 | - | - | - |
Kasey Keller | - | - | 12 | - | - | - |
Nicky Eyre | - | - | 1 | - | - | - | 515 | 418 | 189 | 97 | 97 | 47 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .