| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Jaap Stam | 33 | 33 | - | - | 4 | - |
Dwight Yorke | 32 | 29 | 6 | 3 | 5 | 20 |
Nicky Butt | 32 | 21 | 12 | 11 | 4 | 3 |
Mikael Silvestre | 31 | 30 | 1 | 1 | 2 | - |
David Beckham | 31 | 30 | 2 | 1 | 7 | 6 |
Paul Scholes | 31 | 27 | 6 | 4 | 7 | 9 |
Ryan Giggs | 30 | 30 | 2 | - | 9 | 6 |
Roy Keane | 29 | 28 | 1 | 1 | 5 | 5 |
Phil Neville | 29 | 25 | 12 | 4 | 4 | - |
Andrew Cole | 28 | 23 | 7 | 5 | 9 | 19 |
Ole-Gunnar Solskjaer | 28 | 15 | 20 | 13 | 8 | 12 |
Teddy Sheringham | 27 | 15 | 19 | 12 | 5 | 5 |
Denis Irwin | 25 | 25 | 2 | - | 7 | 3 |
Mark Bosnich | 23 | 23 | 3 | - | 3 | - |
Gary Neville | 22 | 22 | - | - | 3 | - |
Henning Berg | 22 | 16 | 14 | 6 | - | 1 |
Raimonde van der Gouw | 14 | 11 | 24 | 3 | 1 | - |
Jordi Cruyff | 8 | 1 | 13 | 7 | 1 | 3 |
Quinton Fortune | 6 | 4 | 8 | 2 | 1 | 2 |
Ronnie Wallwork | 5 | - | 8 | 5 | - | - |
Massimo Taibi | 4 | 4 | 3 | - | - | - |
Jonathan Greening | 4 | 1 | 5 | 3 | 1 | - |
Danny Higginbotham | 3 | 2 | 2 | 1 | 2 | - |
Ronny Johnsen | 3 | 2 | 1 | 1 | 1 | - |
Mark Wilson | 3 | 1 | 4 | 2 | 1 | - |
Michael Clegg | 2 | - | 3 | 2 | - | - |
Nicky Culkin | 1 | - | 5 | 1 | - | - |
John Curtis | 1 | - | 5 | 1 | - | - |
David May | 1 | - | 1 | 1 | - | - |
Michael Stewart | - | - | 1 | - | - | - | 508 | 418 | 190 | 90 | 90 | 94 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .