| Players | Clubs | Position | Total | Goals | A |  |
 |
 |
Start | Sub | CO | Off | Pen S | Pen SV | Pen M | Pen C | OG | More |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Bernd Leno | Bayer Leverkusen | Goalkeeper | 34 | 0 | 0 | 1 | 0 | 0 | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | |
| Karim Bellarabi | Bayer Leverkusen | Midfielder | 33 | 12 | 6 | 5 | 0 | 0 | 32 | 1 | 1 | 14 | 0 | 0 | 0 | 0 | 0 | |
| Stefan Kiessling | Bayer Leverkusen | Forward | 33 | 9 | 3 | 4 | 0 | 0 | 31 | 3 | 2 | 13 | 0 | 0 | 0 | 0 | 0 | |
| Hakan Calhanoglu | Bayer Leverkusen | Midfielder | 33 | 8 | 5 | 3 | 0 | 0 | 31 | 2 | 2 | 16 | 0 | 0 | 1 | 0 | 0 | |
| Heung Min Son | Bayer Leverkusen | Forward | 31 | 11 | 2 | 4 | 0 | 0 | 28 | 4 | 3 | 11 | 0 | 0 | 0 | 0 | 0 | |
| Omer Toprak | Bayer Leverkusen | Defender | 29 | 1 | 0 | 10 | 0 | 0 | 27 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Lars Bender | Bayer Leverkusen | Midfielder | 26 | 1 | 3 | 5 | 0 | 0 | 25 | 1 | 1 | 10 | 0 | 0 | 0 | 0 | 0 | |
| Wendell | Bayer Leverkusen | Defender | 26 | 1 | 1 | 8 | 0 | 0 | 25 | 7 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Josip Drmic | Bayer Leverkusen | Forward | 25 | 6 | 1 | 1 | 0 | 0 | 5 | 28 | 20 | 3 | 0 | 0 | 0 | 0 | 0 | |
| Simon Rolfes | Bayer Leverkusen | Midfielder | 24 | 1 | 1 | 4 | 0 | 0 | 13 | 12 | 11 | 7 | 0 | 0 | 0 | 0 | 0 | |
| Julian Brandt | Bayer Leverkusen | Midfielder | 24 | 4 | 2 | 0 | 0 | 0 | 10 | 19 | 14 | 7 | 0 | 0 | 0 | 0 | 0 | |
| Roberto Hilbert | Bayer Leverkusen | Midfielder | 23 | 0 | 5 | 6 | 0 | 0 | 21 | 8 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | |
| Emir Spahic | Bayer Leverkusen | Defender | 22 | 1 | 0 | 7 | 2 | 0 | 22 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Gonzalo Castro | Bayer Leverkusen | Midfielder | 22 | 2 | 7 | 4 | 0 | 0 | 19 | 3 | 3 | 2 | 0 | 0 | 0 | 0 | 0 | |
| Tin Jedvaj | Bayer Leverkusen | Defender | 22 | 2 | 1 | 6 | 0 | 1 | 18 | 4 | 4 | 4 | 0 | 0 | 0 | 0 | 1 | |
| Stefan Reinartz | Bayer Leverkusen | Defender | 17 | 1 | 0 | 2 | 0 | 0 | 9 | 17 | 8 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Kyriakos Papadopoulos | Bayer Leverkusen | Defender | 14 | 2 | 1 | 5 | 0 | 0 | 9 | 8 | 5 | 2 | 0 | 0 | 0 | 0 | 0 | |
| Sebastian Boenisch | Bayer Leverkusen | Defender | 12 | 0 | 1 | 2 | 0 | 0 | 9 | 18 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Giulio Donati | Bayer Leverkusen | Defender | 8 | 0 | 0 | 1 | 0 | 1 | 4 | 19 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Levin Oztunali | Bayer Leverkusen | Midfielder | 6 | 0 | 0 | 0 | 0 | 0 | 2 | 11 | 4 | 2 | 0 | 0 | 0 | 0 | 0 | |
| Robbie Kruse | Bayer Leverkusen | Midfielder | 4 | 0 | 1 | 0 | 0 | 0 | 0 | 11 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Vladen Yurchenko | Bayer Leverkusen | Midfielder | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 16 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Dario Kresic | Bayer Leverkusen | Goalkeeper | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 33 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Lukas Boeder | Bayer Leverkusen | Defender | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| David Yelldell | Bayer Leverkusen | Goalkeeper | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A = Assists,
CS = Clean sheets Full
Sub = Started as a sub,
CO = Came on,
Off = Taken off,
S = Scored,
M = Missed,
Total = Total appearances,
OG = Own goals.