| Players | Clubs | Position | Total | Goals | A |  |
 |
 |
Start | Sub | CO | Off | Pen S | Pen SV | Pen M | Pen C | OG | More |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Bernd Leno | Bayer Leverkusen | Goalkeeper | 34 | 0 | 0 | 0 | 0 | 0 | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | |
| Wendell | Bayer Leverkusen | Defender | 32 | 2 | 2 | 9 | 1 | 0 | 27 | 5 | 5 | 4 | 0 | 0 | 0 | 0 | 0 | |
| Julian Brandt | Bayer Leverkusen | Midfielder | 32 | 3 | 8 | 0 | 0 | 0 | 25 | 8 | 7 | 14 | 0 | 0 | 0 | 0 | 0 | |
| Kevin Kampl | Bayer Leverkusen | Midfielder | 30 | 1 | 2 | 4 | 0 | 0 | 28 | 2 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Benjamin Henrichs | Bayer Leverkusen | Defender | 29 | 0 | 2 | 2 | 0 | 0 | 27 | 5 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | |
| Charles Aranguiz | Bayer Leverkusen | Midfielder | 27 | 2 | 2 | 8 | 1 | 0 | 22 | 8 | 5 | 10 | 1 | 0 | 1 | 0 | 0 | |
| Javier Hernandez | Bayer Leverkusen | Forward | 26 | 11 | 2 | 1 | 0 | 0 | 20 | 8 | 6 | 7 | 0 | 0 | 2 | 0 | 0 | |
| Omer Toprak | Bayer Leverkusen | Defender | 25 | 1 | 0 | 6 | 0 | 0 | 25 | 2 | 0 | 5 | 0 | 0 | 1 | 0 | 0 | |
| Kai Havertz | Bayer Leverkusen | Midfielder | 24 | 4 | 5 | 2 | 0 | 0 | 15 | 12 | 9 | 6 | 0 | 0 | 0 | 0 | 0 | |
| Julian Baumgartlinger | Bayer Leverkusen | Midfielder | 22 | 0 | 1 | 1 | 0 | 0 | 19 | 14 | 3 | 6 | 0 | 0 | 0 | 0 | 1 | |
| Kevin Volland | Bayer Leverkusen | Forward | 22 | 6 | 2 | 3 | 0 | 1 | 16 | 7 | 6 | 4 | 1 | 0 | 0 | 0 | 0 | |
| Admir Mehmedi | Bayer Leverkusen | Forward | 22 | 3 | 0 | 1 | 0 | 0 | 16 | 12 | 6 | 13 | 0 | 0 | 0 | 0 | 0 | |
| Stefan Kiessling | Bayer Leverkusen | Forward | 20 | 4 | 1 | 0 | 0 | 0 | 6 | 17 | 14 | 2 | 1 | 0 | 0 | 0 | 0 | |
| Jonathan Tah | Bayer Leverkusen | Defender | 19 | 1 | 1 | 1 | 0 | 0 | 16 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Aleksander Dragovic | Bayer Leverkusen | Defender | 19 | 0 | 1 | 1 | 0 | 0 | 15 | 14 | 4 | 3 | 0 | 0 | 0 | 0 | 0 | |
| Tin Jedvaj | Bayer Leverkusen | Defender | 18 | 1 | 0 | 3 | 1 | 0 | 16 | 12 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | |
| Karim Bellarabi | Bayer Leverkusen | Midfielder | 16 | 2 | 6 | 4 | 0 | 0 | 14 | 5 | 2 | 7 | 0 | 0 | 0 | 0 | 0 | |
| Hakan Calhanoglu | Bayer Leverkusen | Midfielder | 15 | 6 | 5 | 1 | 0 | 0 | 14 | 2 | 1 | 3 | 1 | 0 | 1 | 0 | 0 | |
| Joel Pohjanpalo | Bayer Leverkusen | Forward | 10 | 6 | 0 | 0 | 0 | 0 | 1 | 17 | 9 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Lars Bender | Bayer Leverkusen | Midfielder | 9 | 0 | 1 | 4 | 0 | 0 | 9 | 1 | 0 | 7 | 0 | 0 | 0 | 0 | 0 | |
| Leon Bailey | Bayer Leverkusen | Midfielder | 8 | 0 | 0 | 1 | 0 | 0 | 0 | 9 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Roberto Hilbert | Bayer Leverkusen | Midfielder | 7 | 0 | 0 | 2 | 0 | 0 | 7 | 6 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Danny Da Costa | Bayer Leverkusen | Defender | 3 | 0 | 1 | 0 | 0 | 0 | 1 | 12 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Vladen Yurchenko | Bayer Leverkusen | Midfielder | 3 | 0 | 0 | 0 | 0 | 0 | 1 | 11 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Kyriakos Papadopoulos | Bayer Leverkusen | Defender | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Lukas Boeder | Bayer Leverkusen | Defender | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Robbie Kruse | Bayer Leverkusen | Midfielder | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Atakan Akkaynak | Bayer Leverkusen | Midfielder | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Ramazan Ozcan | Bayer Leverkusen | Goalkeeper | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 34 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A = Assists,
CS = Clean sheets Full
Sub = Started as a sub,
CO = Came on,
Off = Taken off,
S = Scored,
M = Missed,
Total = Total appearances,
OG = Own goals.