| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Davy Klaassen | 33 | 33 | - | - | 4 | 14 |
Andre Onana | 32 | 32 | - | - | - | - |
Davinson Sanchez | 32 | 32 | 1 | - | 4 | 6 |
Joel Veltman | 30 | 30 | 2 | - | - | - |
Amin Younes | 29 | 28 | 3 | 1 | 10 | 3 |
Nick Viergever | 29 | 27 | 5 | 2 | 2 | 2 |
Kasper Dolberg | 29 | 26 | 4 | 3 | 10 | 16 |
Hakim Ziyech | 28 | 28 | 2 | - | 11 | 7 |
Lasse Schone | 27 | 26 | 7 | 1 | 8 | 7 |
Bertrand Traore | 24 | 22 | 4 | 2 | 13 | 9 |
Daley Sinkgraven | 24 | 21 | 5 | 3 | 10 | 1 |
Donny van de Beek | 19 | 4 | 26 | 15 | 2 | - |
Mateo Cassierra | 17 | 1 | 33 | 16 | 1 | 2 |
Jairo Riedewald | 16 | 11 | 22 | 5 | 1 | - |
Justin Kluivert | 14 | 7 | 11 | 7 | 4 | 2 |
Mitchell Dijks | 12 | 8 | 12 | 4 | 1 | - |
Anwar El-Ghazi | 12 | 7 | 8 | 5 | 4 | - |
Matthijs de Ligt | 11 | 6 | 11 | 5 | 2 | 2 |
Abdelhak Nouri | 9 | 1 | 20 | 8 | - | - |
David Neres | 8 | 5 | 6 | 3 | 1 | 3 |
Nemanja Gudelj | 6 | 5 | 3 | 1 | - | 2 |
Kenny Tete | 5 | 5 | 27 | - | - | - |
Riechedly Bazoer | 5 | 3 | 11 | 2 | 3 | - |
Vaclav Cerny | 5 | 2 | 11 | 3 | 3 | - |
Heiko Westermann | 4 | 1 | 30 | 3 | - | - |
Frenkie de Jong | 4 | 1 | 16 | 3 | - | 1 |
Jasper Cillessen | 2 | 2 | - | - | - | - |
Pelle Clement | 1 | - | 1 | 1 | - | - |
Deyovaisio Zeefuik | 1 | - | 1 | 1 | - | - |
Richairo Zivkovic | - | - | 1 | - | - | - |
Diederik Boer | - | - | 34 | - | - | - |
Carl Eiting | - | - | 1 | - | - | - | 468 | 374 | 318 | 94 | 94 | 77 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .