| # | Players | Clubs | Nationality | GC | More |
|---|---|---|---|---|---|
| 1 | Marcus Hahnemann | Reading | United States | 67 | |
| 2 | Maik Taylor | Birmingham City | Northern Ireland | 55 | |
| 3 | Craig Gordon | Sunderland | Scotland | 55 | |
| 4 | Robert Green | West Ham United | England | 53 | |
| 5 | Scott Carson | Aston Villa | England | 50 | |
| 6 | Christopher Kirkland | Wigan Athletic | England | 50 | |
| 7 | Paul Robinson | Tottenham Hotspur | England | 47 | |
| 8 | Brad Friedel | Blackburn Rovers | United States | 47 | |
| 9 | Mark Schwarzer | Middlesbrough | Australia | 46 | |
| 10 | Shay Given | Newcastle United | Republic of Ireland | 43 | |
| 11 | Jussi Jaaskelainen | Bolton Wanderers | Finland | 43 | |
| 12 | Stephen Bywater | Derby County | England | 41 | |
| 13 | Roy Carroll | Derby County | Northern Ireland | 38 | |
| 14 | Antti Niemi | Fulham | Finland | 38 | |
| 15 | David James | Portsmouth | England | 37 | |
| 16 | Joe Hart | Manchester City | England | 35 | |
| 17 | Tim Howard | Everton | United States | 32 | |
| 18 | Pepe Reina | Liverpool | Spain | 29 | |
| 19 | Manuel Almunia | Arsenal | Spain | 25 | |
| 20 | Steve Harper | Newcastle United | England | 25 |
GC = Goals conceded