| # | Players | Clubs | Nationality | GC | More |
|---|---|---|---|---|---|
| 1 | Hans-Jorg Butt | Bayern Munich | Germany | 16 | |
| 2 | Johnny Leoni | FC Zurich | Switzerland | 14 | |
| 3 | Igor Akinfeev | CSKA Moscow | Russia | 14 | |
| 4 | Allan McGregor | Rangers | Scotland | 14 | |
| 5 | Jens Lehmann | VfB Stuttgart | Germany | 12 | |
| 6 | Steve Mandanda | Olympique Marseille | France | 11 | |
| 7 | Sergio Asenjo | Atletico Madrid | Spain | 10 | |
| 8 | Victor Valdes | Barcelona | Spain | 10 | |
| 9 | Vukasin Poleksic | Debreceni VSC | Montenegro | 10 | |
| 10 | Hugo Lloris | Olympique Lyonnais | France | 10 | |
| 11 | Edwin van der Sar | Manchester United | Netherlands | 9 | |
| 12 | Sebastian Frey | Fiorentina | France | 9 | |
| 13 | Julio Cesar | Internazionale | Brazil | 9 | |
| 14 | Iker Casillas | Real Madrid | Spain | 9 | |
| 15 | Djordje Pantic | Debreceni VSC | Serbia | 9 | |
| 16 | Dionisis Chiotis | APOEL Nicosia | Greece | 8 | |
| 17 | Nir Davidovich | Maccabi Haifa | Israel | 8 | |
| 18 | Diego Benaglio | VfL Wolfsburg | Switzerland | 8 | |
| 19 | Giedrius Arlauskis | Unirea Urziceni | Lithuania | 8 | |
| 20 | Antonios Nikopolidis | Olympiakos | Greece | 8 |
GC = Goals conceded