| # | Players | Clubs | Nationality | GC | More |
|---|---|---|---|---|---|
| 1 | Mattia Perin | Pescara | Italy | 64 | |
| 2 | Gianluca Pegolo | Siena | Italy | 55 | |
| 3 | Jean Francois Gillet | Torino | Belgium | 54 | |
| 4 | Samir Handanovic | Internazionale | Slovenia | 51 | |
| 5 | Michael Agazzi | Cagliari | Italy | 49 | |
| 6 | Sebastian Frey | Genoa | France | 49 | |
| 7 | Andrea Consigli | Atalanta | Italy | 49 | |
| 8 | Stefano Sorrentino | Chievo | Italy | 48 | |
| 9 | Sergio Romero | Sampdoria | Argentina | 42 | |
| 10 | Antonio Mirante | Parma | Italy | 39 | |
| 11 | Zeljko Brkic | Udinese | Serbia | 35 | |
| 12 | Mariano Andujar | Catania | Argentina | 34 | |
| 13 | Federico Marchetti | SS Lazio | Italy | 33 | |
| 14 | Emiliano Viviano | Fiorentina | Italy | 32 | |
| 15 | Federico Agliardi | Bologna | Italy | 32 | |
| 16 | Samir Ujkani | Palermo | Kosovo | 31 | |
| 17 | Maarten Stekelenburg | AS Roma | Netherlands | 30 | |
| 18 | Morgan De Sanctis | Napoli | Italy | 29 | |
| 19 | Christian Abbiati | AC Milan | Italy | 24 | |
| 20 | Mauro Goicoechea | AS Roma | Uruguay | 23 |
GC = Goals conceded