| # | Clubs | P | W | D | L | F | A | GD | Points | More |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  New York Red Bulls | 34 | 22 | 5 | 7 | 62 | 33 | 29 | 71 | |
| 2 | Atlanta United | 34 | 21 | 6 | 7 | 70 | 44 | 26 | 69 | |
| 3 | Sporting Kansas City | 34 | 18 | 8 | 8 | 65 | 40 | 25 | 62 | |
| 4 | Seattle Sounders | 34 | 18 | 5 | 11 | 52 | 37 | 15 | 59 | |
| 5 | Los Angeles FC | 34 | 16 | 9 | 9 | 68 | 52 | 16 | 57 | |
| 6 | FC Dallas | 34 | 16 | 9 | 9 | 52 | 44 | 8 | 57 | |
| 7 | New York City | 34 | 16 | 8 | 10 | 59 | 45 | 14 | 56 | |
| 8 | Portland Timbers | 34 | 15 | 9 | 10 | 54 | 48 | 6 | 54 | |
| 9 | DC United | 34 | 14 | 9 | 11 | 60 | 50 | 10 | 51 | |
| 10 | Columbus Crew | 34 | 14 | 9 | 11 | 43 | 45 | -2 | 51 | |
| 11 | Philadelphia Union | 34 | 15 | 5 | 14 | 49 | 50 | -1 | 50 | |
| 12 | Real Salt Lake | 34 | 14 | 7 | 13 | 55 | 58 | -3 | 49 | |
| 13 | Los Angeles Galaxy | 34 | 13 | 9 | 12 | 66 | 64 | 2 | 48 | |
| 14 | Vancouver Whitecaps | 34 | 13 | 8 | 13 | 54 | 67 | -13 | 47 | |
| 15 | Montreal Impact | 34 | 14 | 4 | 16 | 47 | 53 | -6 | 46 | |
| 16 | New England Revolution | 34 | 10 | 11 | 13 | 49 | 55 | -6 | 41 | |
| 17 | Houston Dynamo | 34 | 10 | 8 | 16 | 58 | 58 | 0 | 38 | |
| 18 | Toronto FC | 34 | 10 | 6 | 18 | 59 | 64 | -5 | 36 | |
| 19 | Minnesota United | 34 | 11 | 3 | 20 | 49 | 71 | -22 | 36 | |
| 20 | Chicago Fire | 34 | 8 | 8 | 18 | 48 | 61 | -13 | 32 | |
| 21 | Colorado Rapids | 34 | 8 | 7 | 19 | 36 | 63 | -27 | 31 | |
| 22 | Orlando City | 34 | 8 | 4 | 22 | 43 | 74 | -31 | 28 | |
| 23 | San Jose Earthquakes | 34 | 4 | 9 | 21 | 49 | 71 | -22 | 21 |
P = Matches played,
W = Matches won,
D = Matches drawn,
L = Matches lost,
F = Goals for,
A = Goals against,
GD = Goal difference,