| 8 | Andriy Shevchenko | Semi-finals | UEFA Champions League 98/99 |
| 8 | Serhiy Rebrov | First Group Stage | UEFA Champions League 99/00 |
| 6 | Serhiy Rebrov | Quarter-finals | UEFA Champions League 97/98 |
| 5 | Andriy Shevchenko | Group Stage | UEFA Champions League 97/98 |
| 4 | Serhiy Rebrov | Group Stage | UEFA Champions League 98/99 |
| 3 | Viktor Leonenko | Group Stage | UEFA Champions League 94/95 |
| 3 | Diogo Rincon | Group Stage | UEFA Champions League 03/04 |
| 3 | Maksim Shatskikh | First Group Stage | UEFA Champions League 02/03 |
| 2 | Viktor Tsyhankov | Group Stage | UEFA Champions League 20/21 |
| 2 | Vitali Buyalsky | Group Stage | UEFA Champions League 15/16 |
| 2 | Andriy Yarmolenko | Group Stage | UEFA Champions League 15/16 |
| 2 | Brown Ideye | Group Stage | UEFA Champions League 12/13 |
| 2 | Yuriy Maksimov | Group Stage | UEFA Champions League 97/98 |
| 2 | Ismael Bangoura | Group Stage | UEFA Champions League 07/08 |
| 2 | Maksim Shatskikh | Group Stage | UEFA Champions League 06/07 |
| 2 | Florin Cernat | Group Stage | UEFA Champions League 04/05 |
| 2 | Diogo Rincon | Group Stage | UEFA Champions League 04/05 |
| 2 | Valyantsin Byalkevich | Group Stage | UEFA Champions League 03/04 |
| 2 | Maksim Shatskikh | Group Stage | UEFA Champions League 03/04 |
| 2 | Aleksandr Khatskevich | First Group Stage | UEFA Champions League 02/03 |
| 2 | Aleksandr Khatskevich | Second Group Stage | UEFA Champions League 99/00 |
| 2 | Alexander Melaschenko | First Group Stage | UEFA Champions League 01/02 |
| 2 | Tiberiu Ghioane | First Group Stage | UEFA Champions League 01/02 |
| 2 | Maksim Shatskikh | First Group Stage | UEFA Champions League 00/01 |
| 2 | Georgi Demetradze | First Group Stage | UEFA Champions League 00/01 |
| 1 | Denys Garmash | Group Stage | UEFA Champions League 21/22 |
| 1 | Carlos de Pena | Group Stage | UEFA Champions League 20/21 |
| 1 | Denys Popov | Group Stage | UEFA Champions League 20/21 |
| 1 | Denys Garmash | Group Stage | UEFA Champions League 16/17 |
| 1 | Derlis Gonzalez | Group Stage | UEFA Champions League 16/17 |
| 1 | Viktor Tsyhankov | Group Stage | UEFA Champions League 16/17 |
| 1 | Vitali Buyalsky | Group Stage | UEFA Champions League 16/17 |
| 1 | Andriy Yarmolenko | Group Stage | UEFA Champions League 16/17 |
| 1 | Junior Moraes | Group Stage | UEFA Champions League 16/17 |
| 1 | Serhiy Sydorchuk | Group Stage | UEFA Champions League 16/17 |
| 1 | Artem Besedin | Group Stage | UEFA Champions League 16/17 |
| 1 | Junior Moraes | Group Stage | UEFA Champions League 15/16 |
| 1 | Oleh Gusev | Group Stage | UEFA Champions League 15/16 |
| 1 | Aleksander Dragovic | Group Stage | UEFA Champions League 15/16 |
| 1 | Derlis Gonzalez | Group Stage | UEFA Champions League 15/16 |
| 1 | Denys Garmash | Group Stage | UEFA Champions League 15/16 |
| 1 | Andriy Yarmolenko | Group Stage | UEFA Champions League 12/13 |
| 1 | Miguel Veloso | Group Stage | UEFA Champions League 12/13 |
| 1 | Oleh Gusev | Group Stage | UEFA Champions League 12/13 |
| 1 | Ayila Yussuf | Group Stage | UEFA Champions League 09/10 |
| 1 | Artem Milevskiy | Group Stage | UEFA Champions League 09/10 |
| 1 | Gerson Magrao | Group Stage | UEFA Champions League 09/10 |
| 1 | Taras Mykhalyk | Group Stage | UEFA Champions League 09/10 |
| 1 | Oleh Gusev | Group Stage | UEFA Champions League 09/10 |
| 1 | Andriy Shevchenko | Group Stage | UEFA Champions League 09/10 |
| 1 | Oleksandr Aliyev | Group Stage | UEFA Champions League 08/09 |
| 1 | Artem Milevskiy | Group Stage | UEFA Champions League 08/09 |
| 1 | Roman Eremenko | Group Stage | UEFA Champions League 08/09 |
| 1 | Ismael Bangoura | Group Stage | UEFA Champions League 08/09 |
| 1 | Serhiy Rebrov | Group Stage | UEFA Champions League 94/95 |
| 1 | Andriy Shevchenko | Group Stage | UEFA Champions League 94/95 |
| 1 | Vitali Kossovsky | Semi-finals | UEFA Champions League 98/99 |
| 1 | Kakha Kaladze | Group Stage | UEFA Champions League 98/99 |
| 1 | Oleksandr Holovko | Group Stage | UEFA Champions League 98/99 |
| 1 | Vladyslav Vashchuk | Group Stage | UEFA Champions League 98/99 |
