| Goals | Players | Sections | Competition |
|---|---|---|---|
| 3 | Asamoah Gyan | Group Section | 2010 FIFA World Cup |
| 2 | Mohammed Kudus | Group Section | 2022 FIFA World Cup |
| 2 | Asamoah Gyan | Group Stage | 2014 FIFA World Cup |
| 2 | Andre Ayew | Group Stage | 2014 FIFA World Cup |
| 1 | Andre Ayew | Group Section | 2022 FIFA World Cup |
| 1 | Osman Bukari | Group Section | 2022 FIFA World Cup |
| 1 | Mohammed Salisu | Group Section | 2022 FIFA World Cup |
| 1 | Kevin-Prince Boateng | Last 16 | 2010 FIFA World Cup |
| 1 | Sulley Muntari | Quarter Finals | 2010 FIFA World Cup |
| 1 | Sulley Muntari | Group Stage | 2006 FIFA World Cup |
| 1 | Asamoah Gyan | Group Stage | 2006 FIFA World Cup |
| 1 | Stephen Appiah | Group Stage | 2006 FIFA World Cup |
| 1 | Haminu Draman | Group Stage | 2006 FIFA World Cup |
2022 FIFA World Cup Top goal scorers