| A(D) | Clubs | VS | MD | |
|---|---|---|---|---|
| 23(62) | Partizan Belgrade | Sevilla | 03-Dec-2008 | Match Details |
| 23(81) | Dinamo Zagreb | NEC Nijmegen | 23-Oct-2008 | Match Details |
| 24(2) | Spartak Moscow | NEC Nijmegen | 03-Dec-2008 | Match Details |
| 24(79) | Standard Liege | Sampdoria | 03-Dec-2008 | Match Details |
| 24(103) | Manchester City | Paris Saint-Germain | 03-Dec-2008 | Match Details |
| 24(132) | AFC Ajax | Aston Villa | 23-Oct-2008 | Match Details |
| 24(166) | Paris Saint-Germain | FC Schalke 04 | 23-Oct-2008 | Match Details |
| 25(279) | Udinese | Tottenham Hotspur | 23-Oct-2008 | Match Details |
| 25(310) | Aston Villa | MSK Zilina | 04-Dec-2008 | Match Details |
| 25(340) | Tottenham Hotspur | Udinese | 23-Oct-2008 | Match Details |
| 25(12) | Shakhtar Donetsk | Werder Bremen | 20-May-2009 | Match Details |
| 25(13) | Feyenoord | Lech Poznan | 17-Dec-2008 | Match Details |
| 25(111) | Dynamo Kyiv | Shakhtar Donetsk | 07-May-2009 | Match Details |
| 25(111) | CSKA Moscow | Deportivo La Coruna | 23-Oct-2008 | Match Details |
| 25(129) | NEC Nijmegen | Spartak Moscow | 03-Dec-2008 | Match Details |
| 25(161) | AS Nancy | Feyenoord | 23-Oct-2008 | Match Details |
| 26(199) | AS Saint-Etienne | FC Copenhagen | 23-Oct-2008 | Match Details |
| 26(214) | Benfica | Hertha BSC | 23-Oct-2008 | Match Details |
| 26(226) | SC Heerenveen | Sporting Braga | 04-Dec-2008 | Match Details |
| 26(235) | Lech Poznan | Feyenoord | 17-Dec-2008 | Match Details |
| 26(295) | Rosenborg BK | Club Brugge | 23-Oct-2008 | Match Details |
| 26(299) | VfL Wolfsburg | Portsmouth | 04-Dec-2008 | Match Details |
| 26(9) | Werder Bremen | Hamburger SV | 30-Apr-2009 | Match Details |
| 26(12) | Club Brugge | Rosenborg BK | 23-Oct-2008 | Match Details |
| 26(49) | Sevilla | VfB Stuttgart | 23-Oct-2008 | Match Details |
| 27(222) | MSK Zilina | Hamburger SV | 23-Oct-2008 | Match Details |
| 27(260) | FC Schalke 04 | FC Twente | 03-Dec-2008 | Match Details |
| 27(268) | Hertha BSC | Benfica | 23-Oct-2008 | Match Details |
| 27(270) | Galatasaray SK | Hertha BSC | 03-Dec-2008 | Match Details |
| 27(307) | Hamburger SV | Manchester City | 16-Apr-2009 | Match Details |
| 27(10) | Slavia Prague | Hamburger SV | 04-Dec-2008 | Match Details |
| 27(21) | Sporting Braga | SC Heerenveen | 04-Dec-2008 | Match Details |
| 27(37) | FC Twente | FC Schalke 04 | 03-Dec-2008 | Match Details |
| 27(41) | FC Copenhagen | AS Saint-Etienne | 23-Oct-2008 | Match Details |
| 27(91) | Valencia | Club Brugge | 04-Dec-2008 | Match Details |
| 27(99) | Deportivo La Coruna | CSKA Moscow | 23-Oct-2008 | Match Details |
| 27(102) | VfB Stuttgart | Sevilla | 23-Oct-2008 | Match Details |
| 27(129) | Metalist Kharkiv | Olympiakos | 03-Dec-2008 | Match Details |
| 27(130) | Sampdoria | Standard Liege | 03-Dec-2008 | Match Details |
| 27(150) | Racing Santander | FC Twente | 23-Oct-2008 | Match Details |
| 28(318) | Portsmouth | VfL Wolfsburg | 04-Dec-2008 | Match Details |
| 29(225) | Olympiakos | Metalist Kharkiv | 03-Dec-2008 | Match Details |
| 30(152) | AC Milan | SC Heerenveen | 23-Oct-2008 | Match Details |
MD = Match date,
A(D) = Age(Days).