| A(D) | Clubs | VS | MD | |
|---|---|---|---|---|
| 23(80) | FC Sheriff Tiraspol | FC Basel | 18-Aug-2010 | Match Details |
| 24(257) | AFC Ajax | Dynamo Kyiv | 25-Aug-2010 | Match Details |
| 24(43) | Rosenborg BK | FC Copenhagen | 25-Aug-2010 | Match Details |
| 24(85) | RSC Anderlecht | Partizan Belgrade | 18-Aug-2010 | Match Details |
| 24(149) | BSC Young Boys | Tottenham Hotspur | 17-Aug-2010 | Match Details |
| 25(303) | Dynamo Kyiv | AFC Ajax | 17-Aug-2010 | Match Details |
| 26(210) | Tottenham Hotspur | BSC Young Boys | 17-Aug-2010 | Match Details |
| 26(216) | MSK Zilina | Sparta Prague | 17-Aug-2010 | Match Details |
| 26(256) | Sparta Prague | MSK Zilina | 25-Aug-2010 | Match Details |
| 26(269) | FC Basel | FC Sheriff Tiraspol | 18-Aug-2010 | Match Details |
| 26(82) | Salzburg | Hapoel Tel Aviv | 18-Aug-2010 | Match Details |
| 26(137) | Hapoel Tel Aviv | Salzburg | 24-Aug-2010 | Match Details |
| 27(193) | Sampdoria | Werder Bremen | 24-Aug-2010 | Match Details |
| 27(294) | FC Copenhagen | Rosenborg BK | 17-Aug-2010 | Match Details |
| 27(36) | Partizan Belgrade | RSC Anderlecht | 24-Aug-2010 | Match Details |
| 27(73) | Werder Bremen | Sampdoria | 24-Aug-2010 | Match Details |
| 27(151) | Sporting Braga | Sevilla | 24-Aug-2010 | Match Details |
| 28(271) | Sevilla | Sporting Braga | 24-Aug-2010 | Match Details |
| 28(342) | AJ Auxerre | Zenit St Petersburg | 17-Aug-2010 | Match Details |
| 28(80) | Zenit St Petersburg | AJ Auxerre | 17-Aug-2010 | Match Details |
MD = Match date,
A(D) = Age(Days).