| Date | Result | OPP | FS | Home/Away |
|---|---|---|---|---|
| 14-Aug-2021 | lose |  Liverpool | 0-3 | home |
| 21-Aug-2021 | lose |  Manchester City | 5-0 | away |
| 28-Aug-2021 | lose |  Leicester City | 1-2 | home |
| 11-Sep-2021 | lose |  Arsenal | 1-0 | away |
| 18-Sep-2021 | lose |  Watford | 1-3 | home |
| 25-Sep-2021 | lose |  Everton | 2-0 | away |
| 23-Oct-2021 | lose |  Chelsea | 7-0 | away |
| 31-Oct-2021 | lose |  Leeds United | 1-2 | home |
| 20-Nov-2021 | win |  Southampton | 2-1 | home |
| 30-Nov-2021 | draw |  Newcastle United | 1-1 | away |
| 05-Dec-2021 | lose |  Tottenham Hotspur | 3-0 | away |
| 11-Dec-2021 | lose |  Manchester United | 0-1 | home |
| 14-Dec-2021 | lose |  Aston Villa | 0-2 | home |
| 26-Dec-2021 | lose | Arsenal | 0-5 | home |
| 28-Dec-2021 | lose |  Crystal Palace | 3-0 | away |
| 12-Jan-2022 | lose |  West Ham United | 2-0 | away |
| 12-Feb-2022 | lose | Manchester City | 0-4 | home |
| 25-Feb-2022 | lose | Southampton | 2-0 | away |
| 05-Mar-2022 | lose |  Brentford | 1-3 | home |
| 10-Mar-2022 | lose | Chelsea | 1-3 | home |
| 13-Mar-2022 | lose | Leeds United | 2-1 | away |
| 16-Apr-2022 | lose | Manchester United | 3-2 | away |
| 23-Apr-2022 | lose | Newcastle United | 0-3 | home |
| 30-Apr-2022 | lose | Aston Villa | 2-0 | away |
| 08-May-2022 | lose | West Ham United | 0-4 | home |
| 11-May-2022 | lose | Leicester City | 3-0 | away |
| 22-May-2022 | lose | Tottenham Hotspur | 0-5 | home |
Overall ( 1 wins,1 draw,25 lost )
Home ( 1 wins,0 draw,13 lost )
Away ( 0 wins,1 draw,12 lost )
OPP = Opposition,
FS = Final score.