| Players | Clubs | Position | Total | Goals | A |  |
 |
 |
Start | Sub | CO | Off | Pen S | Pen SV | Pen M | Pen C | OG | More |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Moussa Diaby | Bayer Leverkusen | Midfielder | 6 | 1 | 0 | 2 | 0 | 0 | 6 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | |
| Jonathan Tah | Bayer Leverkusen | Defender | 6 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Lukas Hradecky | Bayer Leverkusen | Goalkeeper | 6 | 0 | 0 | 0 | 0 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | |
| Amine Adli | Bayer Leverkusen | Midfielder | 6 | 1 | 0 | 0 | 0 | 0 | 5 | 1 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | |
| Jeremie Frimpong | Bayer Leverkusen | Defender | 5 | 0 | 2 | 0 | 0 | 0 | 5 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Florian Wirtz | Bayer Leverkusen | Midfielder | 5 | 2 | 1 | 1 | 0 | 0 | 4 | 1 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | |
| Exequiel Palacios | Bayer Leverkusen | Midfielder | 5 | 1 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | |
| Lucas Alario | Bayer Leverkusen | Forward | 5 | 1 | 0 | 1 | 0 | 0 | 4 | 1 | 1 | 4 | 1 | 0 | 0 | 0 | 0 | |
| Kerem Demirbay | Bayer Leverkusen | Midfielder | 4 | 0 | 0 | 1 | 0 | 0 | 4 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Charles Aranguiz | Bayer Leverkusen | Midfielder | 4 | 1 | 0 | 0 | 0 | 0 | 3 | 1 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | |
| Mitchel Bakker | Bayer Leverkusen | Defender | 4 | 0 | 1 | 2 | 0 | 0 | 3 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Paulinho | Bayer Leverkusen | Forward | 4 | 0 | 1 | 0 | 0 | 0 | 2 | 4 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Karim Bellarabi | Bayer Leverkusen | Midfielder | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Piero Hincapie | Bayer Leverkusen | Defender | 3 | 1 | 0 | 0 | 0 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Edmond Tapsoba | Bayer Leverkusen | Defender | 3 | 0 | 0 | 1 | 0 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Robert Andrich | Bayer Leverkusen | Midfielder | 3 | 1 | 0 | 1 | 0 | 0 | 2 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Odilon Kossounou | Bayer Leverkusen | Defender | 3 | 0 | 1 | 0 | 0 | 0 | 2 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Patrik Schick | Bayer Leverkusen | Forward | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Timothy Fosu-Mensah | Bayer Leverkusen | Defender | 2 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Pedro Hincapie Reyna | Bayer Leverkusen | Defender | 2 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Nadiem Amiri | Bayer Leverkusen | Midfielder | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Sardar Azmoun | Bayer Leverkusen | Forward | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Daley Sinkgraven | Bayer Leverkusen | Midfielder | 1 | 0 | 0 | 0 | 0 | 0 | 1 | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | |
| Panagiotis Retsos | Bayer Leverkusen | Defender | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Maximilian Neutgens | Bayer Leverkusen | Goalkeeper | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Emrehan Gedikli | Bayer Leverkusen | Forward | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Lennart Grill | Bayer Leverkusen | Goalkeeper | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Andrey Lunyov | Bayer Leverkusen | Goalkeeper | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |
| Niklas Lomb | Bayer Leverkusen | Goalkeeper | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
A = Assists,
CS = Clean sheets Full
Sub = Started as a sub,
CO = Came on,
Off = Taken off,
S = Scored,
M = Missed,
Total = Total appearances,
OG = Own goals.