| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 John O'Shea | 14 | 11 | 3 | 3 | 3 | - |
Ryan Giggs | 13 | 11 | 2 | 2 | 7 | 5 |
Ole-Gunnar Solskjaer | 12 | 8 | 5 | 4 | 1 | 3 |
Mikael Silvestre | 11 | 11 | - | - | 3 | - |
David Beckham | 11 | 8 | 3 | 3 | 2 | 2 |
Diego Forlan | 11 | 5 | 9 | 6 | 3 | 1 |
Rio Ferdinand | 10 | 10 | - | - | - | - |
Fabian Barthez | 10 | 10 | - | - | 1 | - |
Phil Neville | 10 | 9 | 4 | 1 | 1 | - |
Gary Neville | 10 | 8 | 3 | 2 | 1 | 1 |
Juan Sebastian Veron | 9 | 9 | - | - | 3 | 4 |
Paul Scholes | 9 | 8 | 1 | 1 | 2 | 1 |
Ruud van Nistelrooy | 9 | 8 | 2 | 1 | 4 | 12 |
Nicky Butt | 8 | 8 | - | - | - | - |
Laurent Blanc | 7 | 7 | 2 | - | 3 | 1 |
Quinton Fortune | 6 | 3 | 4 | 3 | - | - |
Wes Brown | 5 | 5 | - | - | 1 | 1 |
Kieran Richardson | 5 | 2 | 5 | 3 | 2 | - |
Roy Keane | 4 | 4 | - | - | 1 | - |
Ricardo | 4 | 3 | 11 | 1 | - | - |
Danny Pugh | 3 | 1 | 8 | 2 | - | - |
Luke Chadwick | 3 | - | 5 | 3 | - | - |
Darren Fletcher | 2 | 2 | 4 | - | 1 | - |
Lee Roche | 1 | 1 | 3 | - | 1 | - |
Roy Carroll | 1 | 1 | 3 | - | - | - |
Mark Lynch | 1 | 1 | 1 | - | - | - |
Michael Stewart | 1 | - | 6 | 1 | - | - |
David May | 1 | - | 7 | 1 | - | - |
Danny Webber | 1 | - | 2 | 1 | - | - |
Daniel Nardiello | 1 | - | 3 | 1 | - | - |
Mads Timm | 1 | - | 1 | 1 | - | - |
Jimmy Davis | - | - | 1 | - | - | - | 194 | 154 | 98 | 40 | 40 | 31 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .