| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 John Terry | 36 | 36 | - | - | - | 4 |
Frank Lampard | 35 | 35 | - | - | - | 16 |
Petr Cech | 34 | 34 | 2 | - | 1 | - |
William Gallas | 34 | 33 | 1 | 1 | 1 | 5 |
Joe Cole | 34 | 26 | 8 | 8 | 18 | 8 |
Claude Makelele | 31 | 29 | 2 | 2 | 3 | - |
Michael Essien | 31 | 27 | 4 | 4 | 5 | 2 |
Hernan Crespo | 30 | 20 | 12 | 10 | 15 | 10 |
Didier Drogba | 29 | 20 | 9 | 9 | 11 | 12 |
Arjen Robben | 28 | 21 | 7 | 7 | 10 | 6 |
Damien Duff | 28 | 18 | 11 | 10 | 14 | 3 |
Shaun Wright-Phillips | 27 | 10 | 19 | 17 | 10 | - |
Eidur Gudjohnsen | 26 | 16 | 12 | 10 | 10 | 2 |
Asier Del Horno | 25 | 25 | 3 | - | 7 | 1 |
Ricardo Carvalho | 24 | 22 | 5 | 2 | 2 | 1 |
Paulo Ferreira | 21 | 18 | 7 | 3 | - | - |
Geremi | 15 | 8 | 9 | 7 | 2 | 2 |
Robert Huth | 13 | 7 | 16 | 6 | 3 | - |
Carlton Cole | 9 | - | 10 | 9 | - | - |
Maniche | 8 | 3 | 7 | 5 | - | - |
Glen Johnson | 4 | 4 | 5 | - | 1 | - |
Carlo Cudicini | 4 | 3 | 33 | 1 | - | - |
Lassana Diarra | 3 | 2 | 2 | 1 | - | - |
Lenny Pidgeley | 1 | 1 | 2 | - | - | - |
Jimmy Smith | 1 | - | 1 | 1 | - | - |
Wayne Bridge | - | - | 1 | - | - | - |
Michael Mancienne | - | - | 1 | - | - | - | 531 | 418 | 189 | 113 | 113 | 72 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .