| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Leighton Baines | 35 | 35 | - | - | 1 | 3 |
Emmerson Boyce | 34 | 34 | - | - | 2 | - |
Emile Heskey | 34 | 33 | 1 | 1 | 11 | 8 |
Denny Landzaat | 33 | 29 | 8 | 4 | 11 | 2 |
Kevin Kilbane | 31 | 26 | 9 | 5 | 6 | 1 |
Lee McCulloch | 29 | 25 | 5 | 4 | 2 | 4 |
Josip Skoko | 28 | 24 | 5 | 4 | 6 | - |
Christopher Kirkland | 26 | 26 | - | - | 1 | - |
Paul Scharner | 25 | 22 | 3 | 3 | - | 3 |
Fitz Hall | 24 | 22 | 2 | 2 | 5 | - |
Henri Camara | 23 | 18 | 7 | 5 | 6 | 6 |
Luis Antonio Valencia | 22 | 17 | 6 | 5 | 10 | 1 |
Arjan de Zeeuw | 21 | 21 | - | - | 2 | - |
Matt Jackson | 20 | 17 | 13 | 3 | 2 | 1 |
Ryan Taylor | 16 | 12 | 5 | 4 | 4 | 1 |
David Cotterill | 16 | 5 | 17 | 11 | 4 | 1 |
Caleb Folan | 13 | 8 | 5 | 5 | 3 | 2 |
Gary Teale | 12 | 7 | 6 | 5 | 6 | - |
David Wright | 12 | 6 | 7 | 6 | 1 | - |
Andreas Johansson | 12 | 4 | 16 | 8 | 1 | - |
John Filan | 10 | 10 | 10 | - | - | - |
David Unsworth | 10 | 6 | 9 | 4 | 2 | 1 |
Julius Aghahowa | 6 | 3 | 6 | 3 | 3 | - |
Svetoslav Todorov | 5 | 2 | 5 | 3 | 1 | - |
Andy Webster | 4 | 3 | 4 | 1 | 2 | - |
Mike Pollitt | 3 | 2 | 21 | 1 | - | - |
Kristofer Haestad | 2 | 1 | 2 | 1 | 1 | - |
Graham Kavanagh | 2 | - | 2 | 2 | - | - |
David Connolly | 2 | - | 2 | 2 | - | - |
Pascal Chimbonda | 1 | - | 1 | 1 | - | - |
Andreas Granqvist | - | - | 3 | - | - | - |
Tomasz Cywka | - | - | 3 | - | - | - |
Carlo Nash | - | - | 7 | - | - | - | 511 | 418 | 190 | 93 | 93 | 34 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .