| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Joe Cole | 33 | 28 | 9 | 5 | 18 | 7 |
Salomon Kalou | 30 | 24 | 7 | 6 | 7 | 7 |
Mikel John Obi | 29 | 21 | 8 | 8 | 3 | - |
Alex Costa | 28 | 22 | 12 | 6 | - | 2 |
Ashley Cole | 27 | 27 | - | - | 2 | 1 |
Michael Essien | 27 | 23 | 4 | 4 | 3 | 6 |
Shaun Wright-Phillips | 27 | 20 | 9 | 7 | 14 | 2 |
Petr Cech | 26 | 26 | - | - | 1 | - |
Frank Lampard | 24 | 23 | 1 | 1 | 3 | 10 |
John Terry | 23 | 23 | - | - | 3 | 1 |
Juliano Belletti | 23 | 20 | 5 | 3 | 1 | 2 |
Ricardo Carvalho | 21 | 21 | 1 | - | 3 | 1 |
Florent Malouda | 21 | 16 | 5 | 5 | 10 | 2 |
Claudio Pizarro | 21 | 4 | 19 | 17 | 4 | 2 |
Didier Drogba | 19 | 17 | 3 | 2 | 5 | 8 |
Michael Ballack | 18 | 16 | 4 | 2 | 5 | 7 |
Claude Makelele | 18 | 15 | 5 | 3 | 6 | - |
Paulo Ferreira | 18 | 15 | 7 | 3 | 3 | - |
Andriy Shevchenko | 17 | 8 | 16 | 9 | 4 | 5 |
Steve Sidwell | 15 | 7 | 9 | 8 | 5 | - |
Nicolas Anelka | 14 | 10 | 4 | 4 | 1 | 1 |
Tal Ben Haim | 13 | 10 | 16 | 3 | - | - |
Wayne Bridge | 11 | 9 | 4 | 2 | - | - |
Carlo Cudicini | 10 | 10 | 22 | - | - | - |
Hilario | 3 | 2 | 14 | 1 | - | - |
Glen Johnson | 2 | 1 | 1 | 1 | - | - |
Scott Sinclair | 1 | - | 3 | 1 | - | - |
Rhys Taylor | - | - | 2 | - | - | - | 519 | 418 | 190 | 101 | 101 | 64 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .