| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Daniele De Rossi | 10 | 9 | 1 | 1 | 1 | - |
David Pizarro | 10 | 7 | 3 | 3 | 2 | 1 |
Philippe Mexes | 9 | 9 | - | - | 1 | - |
Doni | 9 | 9 | - | - | - | - |
Mancini | 9 | 9 | 1 | - | 4 | 2 |
Ludovic Giuly | 9 | 5 | 5 | 4 | 3 | 1 |
Juan | 8 | 8 | 1 | - | 2 | 1 |
Max Tonetto | 8 | 6 | 2 | 2 | 1 | - |
Mirko Vucinic | 8 | 4 | 6 | 4 | 1 | 4 |
Marco Cassetti | 7 | 7 | - | - | 1 | 1 |
Cicinho | 7 | 4 | 6 | 3 | 1 | - |
Simone Perrotta | 6 | 6 | - | - | 2 | 1 |
Francesco Totti | 6 | 6 | - | - | 1 | 1 |
Rodrigo Taddei | 6 | 6 | 1 | - | 4 | 1 |
Christian Panucci | 6 | 5 | 2 | 1 | 1 | 1 |
Mauro Esposito | 6 | 1 | 5 | 5 | 1 | - |
Alberto Aquilani | 5 | 4 | 2 | 1 | 3 | - |
Matteo Ferrari | 5 | 2 | 6 | 3 | - | - |
Ahmed Barusso | 2 | 1 | 4 | 1 | 1 | - |
Matteo Brighi | 2 | - | 7 | 2 | - | - |
Vitorino Antunes | 1 | 1 | 5 | - | - | - |
Gianluca Curci | 1 | 1 | 6 | - | - | - |
Adrian Pit | - | - | 3 | - | - | - |
Julio Sergio | - | - | 4 | - | - | - | 140 | 110 | 70 | 30 | 30 | 14 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .