| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Diego Lopez | 10 | 9 | 1 | 1 | 1 | - |
Santi Cazorla | 7 | 5 | 1 | 2 | 2 | 1 |
Jon Dahl Tomasson | 6 | 5 | 1 | 1 | 2 | 4 |
Diego Godin | 5 | 5 | - | - | - | - |
Joan Capdevila | 5 | 4 | 1 | 1 | 1 | 1 |
Guillermo Franco | 5 | 1 | 4 | 4 | - | 1 |
Matias Fernandez | 4 | 4 | - | - | - | - |
Josico | 4 | 4 | - | - | 2 | - |
Nihat Kahveci | 4 | 3 | 3 | 1 | 3 | 1 |
Pascal Cygan | 4 | 3 | 3 | 1 | - | - |
Giuseppe Rossi | 4 | 3 | 1 | 1 | 2 | - |
Bruno Soriano | 4 | 2 | 2 | 2 | 1 | - |
Marcos Senna | 3 | 3 | 2 | - | 2 | - |
Josemi | 3 | 3 | 2 | - | - | - |
Rio Mavuba | 3 | 3 | 1 | - | - | 1 |
Cani | 3 | 2 | 4 | 1 | 1 | - |
Gonzalo Rodriguez | 2 | 2 | - | - | - | - |
Fabricio Fuentas | 2 | 2 | 2 | - | - | - |
Javi Venta | 2 | 1 | 3 | 1 | - | - |
Robert Pires | 2 | 1 | 3 | 1 | - | - |
Angel Lopez | 1 | 1 | 1 | - | - | - |
Sebastian Viera | - | - | 6 | - | - | - | 83 | 66 | 41 | 17 | 17 | 9 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .