| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Doni | 8 | 8 | - | - | - | - |
John Arne Riise | 8 | 6 | 2 | 2 | 2 | - |
Mirko Vucinic | 8 | 5 | 3 | 3 | 2 | 3 |
Daniele De Rossi | 7 | 7 | - | - | - | - |
Matteo Brighi | 7 | 6 | 2 | 1 | 2 | 3 |
Rodrigo Taddei | 7 | 6 | 1 | 1 | 3 | - |
Francesco Totti | 7 | 6 | 1 | 1 | 3 | 2 |
Julio Baptista | 7 | 4 | 3 | 3 | 1 | 2 |
Philippe Mexes | 6 | 6 | - | - | - | - |
Simone Perrotta | 6 | 5 | 1 | 1 | 3 | - |
Christian Panucci | 5 | 5 | - | - | 1 | 2 |
Cicinho | 5 | 4 | 1 | 1 | - | - |
David Pizarro | 5 | 2 | 3 | 3 | - | - |
Juan | 4 | 4 | - | - | 1 | 1 |
Alberto Aquilani | 4 | 3 | 1 | 1 | 2 | - |
Max Tonetto | 4 | 3 | 3 | 1 | 1 | - |
Jeremy Menez | 3 | 2 | 5 | 1 | 2 | - |
Marco Cassetti | 2 | 2 | 1 | - | - | - |
Marco Motta | 2 | 2 | - | - | - | - |
Simone Loria | 2 | 1 | 7 | 1 | 1 | - |
Souleymane Diamoutene | 2 | 1 | 1 | 1 | - | - |
Vincenzo Montella | 2 | - | 7 | 2 | - | - |
Stefano Okaka | 1 | - | 3 | 1 | - | - |
Filipe | - | - | 3 | - | - | - |
Artur Moraes | - | - | 8 | - | - | - | 112 | 88 | 56 | 24 | 24 | 13 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .