| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Tim Howard | 38 | 38 | - | - | - | - |
Leighton Baines | 37 | 37 | - | - | - | 1 |
Tim Cahill | 33 | 33 | - | - | 6 | 8 |
Louis Saha | 33 | 26 | 7 | 7 | 18 | 13 |
John Heitinga | 31 | 29 | 2 | 2 | 2 | - |
Steven Pienaar | 30 | 30 | - | - | 5 | 4 |
Sylvain Distin | 29 | 29 | - | - | 1 | - |
Leon Osman | 26 | 25 | 1 | 1 | 15 | 2 |
Jack Rodwell | 26 | 17 | 11 | 9 | 5 | 2 |
Aiyegbeni Yakubu | 25 | 9 | 21 | 16 | 6 | 5 |
Phil Neville | 23 | 22 | 2 | 1 | 2 | - |
Marouane Fellaini | 23 | 20 | 3 | 3 | 3 | 2 |
Diniyar Bilyaletdinov | 23 | 16 | 15 | 7 | 9 | 6 |
Tony Hibbert | 20 | 17 | 12 | 3 | 3 | - |
Joseph Yobo | 17 | 14 | 11 | 3 | 2 | 1 |
Jo | 15 | 6 | 9 | 9 | 5 | - |
Mikel Arteta | 13 | 11 | 2 | 2 | 3 | 6 |
Philip Jagielka | 12 | 11 | 1 | 1 | - | - |
Lucas Neill | 12 | 10 | 5 | 2 | - | - |
Victor Anichebe | 11 | 6 | 5 | 5 | 6 | 1 |
Dan Gosling | 11 | 3 | 18 | 8 | 2 | 2 |
Landon Donovan | 10 | 7 | 3 | 3 | 4 | 2 |
James Vaughan | 8 | - | 13 | 8 | - | 1 |
Seamus Coleman | 3 | - | 18 | 3 | - | - |
Philippe Senderos | 2 | 1 | 10 | 1 | - | - |
Jose Baxter | 2 | - | 17 | 2 | - | - |
Joleon Lescott | 1 | 1 | - | - | - | - |
Kieran Agard | 1 | - | 10 | 1 | - | - |
Hope Akpan | - | - | 1 | - | - | - |
Shkodran Mustafi | - | - | 3 | - | - | - |
Adam Forshaw | - | - | 1 | - | - | - |
James Wallace | - | - | 8 | - | - | - |
Shane Duffy | - | - | 18 | - | - | - |
Iain Turner | - | - | 6 | - | - | - |
Carlo Nash | - | - | 32 | - | - | - | 515 | 418 | 265 | 97 | 97 | 56 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .