| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Peter Crouch | 38 | 21 | 17 | 17 | 1 | 8 |
Jermain Defoe | 34 | 31 | 3 | 3 | 18 | 18 |
Tom Huddlestone | 33 | 33 | 1 | - | 5 | 2 |
Wilson Palacios | 33 | 29 | 7 | 4 | 7 | 1 |
Heurelho Gomes | 31 | 31 | 4 | - | 1 | - |
Benoit Assou-Ekotto | 30 | 29 | 2 | 1 | 5 | 1 |
Vedran Corluka | 29 | 29 | 1 | - | 3 | 1 |
Michael Dawson | 29 | 25 | 6 | 4 | 1 | 2 |
Sebastien Bassong | 28 | 25 | 12 | 3 | 3 | 1 |
Luka Modric | 25 | 21 | 5 | 4 | 7 | 3 |
Niko Kranjcar | 24 | 19 | 8 | 5 | 10 | 6 |
Gareth Bale | 23 | 18 | 12 | 5 | - | 3 |
Aaron Lennon | 22 | 20 | 2 | 2 | 5 | 3 |
Ledley King | 20 | 19 | 1 | 1 | 5 | 2 |
Robbie Keane | 20 | 15 | 9 | 5 | 12 | 6 |
Jermaine Jenas | 19 | 9 | 16 | 10 | 1 | 1 |
Roman Pavlyuchenko | 16 | 8 | 21 | 8 | 7 | 5 |
David Bentley | 15 | 11 | 17 | 4 | 4 | 2 |
Eidur Gudjohnsen | 11 | 3 | 11 | 8 | 2 | 1 |
Younes Kaboul | 10 | 8 | 6 | 2 | - | - |
Alan Hutton | 8 | 1 | 21 | 7 | - | - |
Carlo Cudicini | 7 | 6 | 4 | 1 | - | - |
Jonathan Woodgate | 3 | 3 | 1 | - | 1 | - |
Kyle Walker | 2 | 2 | 6 | - | - | - |
Jamie O'Hara | 2 | - | 4 | 2 | - | - |
Ben Alnwick | 1 | 1 | 26 | - | - | - |
Danny Rose | 1 | 1 | 12 | - | 1 | 1 |
Kyle Naughton | 1 | - | 10 | 1 | - | - |
Giovani Dos Santos | 1 | - | 4 | 1 | - | - |
Jake Livermore | 1 | - | 6 | 1 | - | - |
David Button | - | - | 3 | - | - | - |
Dorian Dervite | - | - | 3 | - | - | - |
Dean Parrett | - | - | 1 | - | - | - |
Andros Townsend | - | - | 2 | - | - | - |
Pascal Chimbonda | - | - | 1 | - | - | - |
Jimmy Walker | - | - | 1 | - | - | - | 517 | 418 | 266 | 99 | 99 | 67 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .