| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Robert Green | 38 | 38 | - | - | 1 | - |
Matthew Upson | 33 | 33 | - | - | 1 | 3 |
Julian Faubert | 33 | 32 | 4 | 1 | 2 | 1 |
Scott Parker | 31 | 30 | 1 | 1 | 5 | 2 |
Radoslav Kovac | 31 | 27 | 8 | 4 | 10 | 2 |
Carlton Cole | 30 | 26 | 4 | 4 | 6 | 10 |
Mark Noble | 27 | 25 | 6 | 2 | 6 | 2 |
Valon Behrami | 27 | 24 | 3 | 3 | 7 | 1 |
Jonathan Spector | 27 | 22 | 16 | 5 | 1 | - |
Alessandro Diamanti | 27 | 18 | 13 | 9 | 7 | 7 |
Junior Stanislas | 26 | 11 | 24 | 15 | 5 | 3 |
James Tomkins | 23 | 22 | 7 | 1 | 2 | - |
Guillermo Franco | 23 | 16 | 7 | 7 | 10 | 5 |
Jack Collison | 22 | 19 | 5 | 3 | 8 | 2 |
Herita Ilunga | 16 | 16 | 4 | - | 5 | - |
Manuel Da Costa | 15 | 12 | 18 | 3 | - | 2 |
Zavon Hines | 13 | 5 | 10 | 8 | 2 | 1 |
Luis Jimenez | 11 | 6 | 10 | 5 | 4 | 1 |
Ilan | 11 | 6 | 9 | 5 | 4 | 4 |
Daniel Gabbidon | 10 | 8 | 12 | 2 | 1 | - |
Kieron Dyer | 10 | 4 | 6 | 6 | 4 | - |
Hossam Mido | 9 | 5 | 6 | 4 | 5 | - |
Frank Nouble | 8 | 3 | 15 | 5 | 3 | - |
Fabio Daprela | 7 | 4 | 12 | 3 | - | - |
Benni McCarthy | 5 | 2 | 8 | 3 | 2 | - |
James Collins | 3 | 3 | - | - | - | - |
Luis Boa Morte | 1 | 1 | 1 | - | 1 | 1 |
Peter Kurucz | 1 | - | 25 | 1 | - | - |
Freddie Sears | 1 | - | 3 | 1 | - | - |
Jordan Spence | 1 | - | 4 | 1 | - | - |
Marek Stech | - | - | 13 | - | - | - |
Josh Payne | - | - | 11 | - | - | - |
Bondz N'Gala | - | - | 1 | - | - | - | 520 | 418 | 266 | 102 | 102 | 47 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .