| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Frederic Piquionne | 34 | 26 | 9 | 8 | 12 | 5 |
Marc Wilson | 28 | 28 | 4 | - | 3 | - |
Jamie O'Hara | 26 | 25 | 1 | 1 | 4 | 2 |
David James | 25 | 25 | - | - | 2 | - |
Michael Brown | 24 | 22 | 4 | 2 | 4 | 2 |
Aaron Mokoena | 23 | 21 | 5 | 2 | 9 | - |
Nwankwo Kanu | 23 | 6 | 22 | 17 | 3 | 2 |
Tal Ben Haim | 22 | 21 | 2 | 1 | - | - |
Kevin-Prince Boateng | 22 | 20 | 2 | 2 | 4 | 3 |
Steve Finnan | 21 | 20 | 4 | 1 | 4 | - |
Younes Kaboul | 19 | 19 | - | - | - | 3 |
Aruna Dindane | 19 | 18 | 4 | 1 | 6 | 8 |
Nadir Belhadj | 19 | 16 | 11 | 3 | 1 | 3 |
Anthony Vanden Borre | 19 | 15 | 11 | 4 | 2 | - |
Hayden Mullins | 18 | 15 | 17 | 3 | 3 | - |
Hassan Yebda | 18 | 15 | 7 | 3 | 7 | 2 |
John Utaka | 18 | 10 | 13 | 8 | 2 | 1 |
Hermann Hreidarsson | 17 | 17 | 1 | - | 3 | 1 |
Danny Webber | 17 | 4 | 18 | 13 | 3 | 1 |
Tommy Smith | 16 | 12 | 7 | 4 | 9 | 1 |
Papa Bouba Diop | 12 | 9 | 8 | 3 | 6 | - |
Angelos Basinas | 12 | 7 | 10 | 5 | 2 | - |
Ricardo Rocha | 10 | 10 | 2 | - | 3 | - |
Richard Hughes | 10 | 9 | 13 | 1 | 4 | - |
Quincy Owusu-Abeyie | 10 | 3 | 8 | 7 | 2 | - |
Asmir Begovic | 9 | 8 | 8 | 1 | - | - |
Jamie Ashdown | 6 | 5 | 25 | 1 | - | - |
Lennard Sowah | 5 | 3 | 4 | 2 | - | - |
Niko Kranjcar | 4 | 4 | - | - | - | - |
Sylvain Distin | 3 | 3 | - | - | - | - |
Joel Ward | 3 | 1 | 9 | 2 | - | - |
Dave Nugent | 3 | - | 4 | 3 | - | - |
Matt Ritchie | 2 | 1 | 10 | 1 | 1 | - |
Antti Niemi | - | - | 1 | - | - | - |
Gael N'Lundulu | - | - | 1 | - | - | - |
Marlon Pack | - | - | 2 | - | - | - |
Liam O'Brien | - | - | 2 | - | - | - |
Nadir Ciftci | - | - | 1 | - | - | - |
Mike Williamson | - | - | 7 | - | - | - | 517 | 418 | 257 | 99 | 99 | 34 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .