| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 John Terry | 37 | 37 | - | - | 2 | 2 |
Frank Lampard | 36 | 36 | - | - | 2 | 22 |
Petr Cech | 34 | 34 | - | - | - | - |
Nicolas Anelka | 33 | 31 | 4 | 2 | 14 | 11 |
Florent Malouda | 33 | 26 | 11 | 7 | 6 | 12 |
Didier Drogba | 32 | 31 | 2 | 1 | 7 | 29 |
Michael Ballack | 32 | 26 | 7 | 6 | 7 | 4 |
Branislav Ivanovic | 28 | 25 | 9 | 3 | 3 | 1 |
Ashley Cole | 27 | 25 | 3 | 2 | 4 | 4 |
Joe Cole | 26 | 14 | 16 | 12 | 9 | 2 |
Mikel John Obi | 25 | 21 | 6 | 4 | 10 | - |
Salomon Kalou | 23 | 11 | 21 | 12 | 10 | 5 |
Ricardo Carvalho | 22 | 22 | 5 | - | 5 | - |
Deco | 19 | 14 | 10 | 5 | 6 | 2 |
Yuri Zhirkov | 17 | 10 | 18 | 7 | 5 | - |
Alex Costa | 16 | 13 | 10 | 3 | - | 1 |
Michael Essien | 14 | 13 | 2 | 1 | - | 3 |
Paulo Ferreira | 13 | 11 | 19 | 2 | 3 | - |
Daniel Sturridge | 13 | 2 | 27 | 11 | 2 | 1 |
Juliano Belletti | 11 | 4 | 16 | 7 | 1 | - |
Jose Bosingwa | 8 | 8 | - | - | 4 | - |
Fabio Borini | 4 | - | 10 | 4 | - | - |
Hilario | 3 | 2 | 25 | 1 | - | - |
Ross Turnbull | 2 | 2 | 11 | - | - | - |
Sam Hutchinson | 2 | - | 5 | 2 | - | - |
Jeffrey Bruma | 2 | - | 9 | 2 | - | - |
Nemanja Matic | 2 | - | 10 | 2 | - | - |
Patrick van Aanholt | 2 | - | 4 | 2 | - | - |
Gael Kakuta | 1 | - | 3 | 1 | - | - |
Andriy Shevchenko | 1 | - | 1 | 1 | - | - |
Jan Sebek | - | - | 1 | - | - | - |
Rhys Taylor | - | - | 1 | - | - | - | 518 | 418 | 266 | 100 | 100 | 99 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .