| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Victor Valdes | 38 | 38 | - | - | - | - |
Lionel Messi | 35 | 30 | 5 | 5 | 4 | 34 |
Xavi | 34 | 31 | 3 | 3 | 8 | 3 |
Pedro Rodriguez | 34 | 22 | 16 | 12 | 11 | 12 |
Sergio Busquets | 33 | 26 | 9 | 7 | 5 | - |
Carles Puyol | 32 | 31 | 5 | 1 | 4 | 1 |
Gerard Pique | 32 | 29 | 3 | 3 | 7 | 2 |
Dani Alves | 29 | 28 | 2 | 1 | 1 | 3 |
Seydou Keita | 29 | 23 | 6 | 6 | 3 | 6 |
Andres Iniesta | 29 | 20 | 10 | 9 | 7 | 1 |
Zlatan Ibrahimovic | 28 | 23 | 8 | 5 | 7 | 16 |
Maxwell | 25 | 25 | 11 | - | 3 | - |
Yaya Toure | 23 | 18 | 14 | 5 | 9 | 1 |
Bojan Krkic | 23 | 11 | 23 | 12 | 7 | 8 |
Thierry Henry | 21 | 15 | 18 | 6 | 10 | 4 |
Eric Abidal | 17 | 15 | 7 | 2 | - | - |
Rafael Marquez (Mex) | 15 | 7 | 22 | 8 | 2 | 1 |
Dmytro Chygrynskiy | 12 | 10 | 20 | 2 | 2 | - |
Jeffren | 12 | 6 | 11 | 6 | 6 | 2 |
Gabriel Milito | 11 | 9 | 15 | 2 | 3 | - |
Jonathan Dos Santos | 3 | 1 | 8 | 2 | 1 | - |
Andreau Fontas | 1 | - | 2 | 1 | - | - |
Thiago Alcantara | 1 | - | 7 | 1 | - | 1 |
Marc Bartra | 1 | - | 1 | 1 | - | - |
Jose Manuel Pinto | - | - | 38 | - | - | - |
Marc Muniesa | - | - | 2 | - | - | - |
Victor Sanchez | - | - | 1 | - | - | - | 518 | 418 | 267 | 100 | 100 | 95 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .