| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Clarence Seedorf | 8 | 7 | 1 | 1 | 3 | - |
Zlatan Ibrahimovic | 8 | 7 | 1 | 1 | 1 | 4 |
Alessandro Nesta | 7 | 7 | - | - | - | - |
Robinho | 7 | 5 | 3 | 2 | 2 | - |
Kevin-Prince Boateng | 7 | 2 | 5 | 5 | 1 | - |
Christian Abbiati | 6 | 6 | - | - | 1 | - |
Thiago Silva | 6 | 6 | - | - | - | - |
Luca Antonini | 6 | 5 | 2 | 1 | 1 | - |
Ignazio Abate | 6 | 4 | 4 | 2 | - | - |
Mathieu Flamini | 5 | 5 | 1 | - | 3 | - |
Gennaro Gattuso | 5 | 5 | 1 | - | 3 | - |
Andrea Pirlo | 5 | 5 | - | - | - | - |
Gianluca Zambrotta | 5 | 5 | - | - | - | - |
Ronaldinho Gaucho | 5 | 4 | 2 | 1 | 2 | 1 |
Alexandre Pato | 5 | 4 | 1 | 1 | 3 | - |
Massimo Ambrosini | 4 | 3 | 1 | 1 | 2 | - |
Daniele Bonera | 3 | 3 | 2 | - | - | - |
Marco Amelia | 3 | 2 | 6 | 1 | - | - |
Filippo Inzaghi | 3 | - | 4 | 3 | - | 2 |
Mario Yepes | 2 | 2 | 3 | - | - | - |
Alexander Merkel | 2 | - | 3 | 2 | - | - |
Rodney Strasser | 2 | - | 3 | 2 | - | - |
Marek Jankulovski | 1 | 1 | 3 | - | 1 | - |
Nicola Legrottaglie | - | - | 1 | - | - | - |
Sokratis Papastathopoulos | - | - | 4 | - | - | - |
Flavio Roma | - | - | 2 | - | - | - |
Massimo Oddo | - | - | 2 | - | - | - | 111 | 88 | 55 | 23 | 23 | 7 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .