| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Nani | 12 | 9 | 3 | 3 | 5 | 1 |
Michael Carrick | 11 | 11 | - | - | 1 | - |
Edwin van der Sar | 10 | 10 | 1 | - | - | - |
Patrice Evra | 10 | 9 | 2 | 1 | 1 | - |
Wayne Rooney | 9 | 9 | - | - | 1 | 4 |
Nemanja Vidic | 9 | 9 | 1 | - | - | - |
Ji Sung Park | 9 | 8 | 1 | 1 | 4 | 1 |
Chris Smalling | 9 | 7 | 6 | 2 | - | - |
Javier Hernandez | 9 | 6 | 7 | 3 | 2 | 4 |
Ryan Giggs | 8 | 6 | 3 | 2 | - | 1 |
Rio Ferdinand | 7 | 7 | - | - | 1 | - |
Rafael Da Silva | 7 | 6 | 3 | 1 | 4 | - |
Dimitar Berbatov | 7 | 6 | 4 | 1 | 3 | - |
Darren Fletcher | 7 | 5 | 3 | 2 | 1 | 1 |
Luis Antonio Valencia | 7 | 5 | 2 | 2 | 1 | 1 |
Fabio Da Silva | 7 | 5 | 3 | 2 | 2 | - |
Paul Scholes | 7 | 4 | 5 | 3 | 2 | - |
John O'Shea | 6 | 5 | 4 | 1 | 1 | - |
Anderson | 6 | 4 | 4 | 2 | 3 | 3 |
Darron Gibson | 3 | 3 | 4 | - | 1 | 1 |
Jonny Evans | 3 | 2 | 3 | 1 | - | - |
Gabriel Obertan | 3 | 1 | 5 | 2 | - | 1 |
Tomasz Kuszczak | 2 | 2 | 10 | - | - | - |
Wes Brown | 2 | 2 | 4 | - | - | - |
Federico Macheda | 2 | 1 | 4 | 1 | - | - |
Michael Owen | 2 | - | 4 | 2 | - | - |
Ben Amos | 1 | 1 | 2 | - | - | - |
Bebe | 1 | - | 2 | 1 | - | 1 |
Gary Neville | - | - | 1 | - | - | - | 176 | 143 | 91 | 33 | 33 | 19 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .