| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 David de Gea | 39 | 39 | - | - | - | - |
Jose Antonio Reyes | 36 | 36 | - | - | 9 | 6 |
Sergio Aguero | 33 | 32 | 1 | 1 | 9 | 20 |
Tomas Ujfalusi | 32 | 32 | - | - | - | - |
Tiago | 32 | 29 | 3 | 3 | 10 | 4 |
Diego Forlan | 32 | 24 | 11 | 8 | 10 | 8 |
Luis Perea | 29 | 29 | 3 | - | 1 | - |
Filipe Luis | 28 | 24 | 12 | 4 | 3 | 1 |
Raul Garcia | 28 | 18 | 18 | 10 | 12 | 1 |
Diego Costa | 28 | 13 | 23 | 15 | 4 | 6 |
Mario Suarez | 27 | 18 | 15 | 9 | 6 | 2 |
Diego Godin | 25 | 25 | 4 | - | 1 | - |
Paulo Assuncao | 25 | 18 | 19 | 7 | 5 | - |
Alvaro Dominguez | 20 | 18 | 15 | 2 | 1 | 2 |
Simao Sabrosa | 17 | 16 | 1 | 1 | 4 | 3 |
Antonio Lopez | 17 | 15 | 22 | 2 | 3 | - |
Jorge Koke | 17 | 8 | 12 | 9 | 6 | 2 |
Fran Merida | 17 | 6 | 18 | 11 | 4 | - |
Juan Valera | 15 | 11 | 16 | 4 | - | 1 |
Elias | 15 | 10 | 8 | 5 | 8 | 2 |
Juanfran | 14 | 5 | 14 | 9 | 3 | 1 |
Jorge Pulido | 2 | 2 | - | - | - | - |
Jose Manuel Jurado | 1 | 1 | - | - | 1 | 1 |
Juanito | - | - | 2 | - | - | - |
Borja Gonzalez | - | - | 3 | - | - | - |
Ignacio Camacho | - | - | 10 | - | - | - |
Alberto Noguera | - | - | 2 | - | - | - |
Joel Robles | - | - | 39 | - | - | - | 529 | 429 | 271 | 100 | 100 | 60 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .