| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Isco | 37 | 36 | 2 | 1 | 13 | 9 |
Willy Caballero | 36 | 36 | 1 | - | 1 | - |
Joaquin | 34 | 29 | 8 | 5 | 20 | 4 |
Weligton | 33 | 33 | 1 | - | - | 2 |
Ignacio Camacho | 33 | 30 | 5 | 3 | 3 | 2 |
Martin Demichelis | 31 | 31 | 1 | - | 1 | 4 |
Roque Santa Cruz | 31 | 15 | 19 | 16 | 5 | 8 |
Jesus Gamez | 28 | 28 | 5 | - | 2 | - |
Eliseu | 28 | 25 | 4 | 3 | 6 | 1 |
Francisco Portillo | 27 | 20 | 10 | 7 | 9 | 2 |
Javier Saviola | 27 | 19 | 15 | 8 | 17 | 8 |
Manuel Iturra | 25 | 15 | 17 | 10 | 7 | - |
Jeremy Toulalan | 19 | 18 | 3 | 1 | 5 | - |
Sergio Sanchez | 18 | 14 | 16 | 4 | - | - |
Sebastian Fernandez | 17 | 5 | 22 | 12 | 4 | - |
Duda | 17 | 3 | 27 | 14 | 1 | - |
Nacho Monreal | 14 | 14 | - | - | 2 | 1 |
Julio Baptista | 14 | 11 | 3 | 3 | 5 | 4 |
Vitorino Antunes | 11 | 10 | 6 | 1 | - | 1 |
Diego Lugano | 11 | 10 | 6 | 1 | - | - |
Lucas Piazon | 11 | 4 | 10 | 7 | 3 | - |
Diego Buonanotte | 9 | 2 | 13 | 7 | 2 | 1 |
Pedro Morales | 7 | 5 | 5 | 2 | 4 | 3 |
Recio | 4 | 1 | 8 | 3 | 1 | - |
Carlos Kameni | 3 | 2 | 32 | 1 | - | - |
Fabrice Olinga | 2 | 1 | 1 | 1 | 1 | 1 |
Oguchi Onyewu | 2 | 1 | 17 | 1 | - | - |
Juanmi | 1 | - | 2 | 1 | - | 1 |
Alex Portillo | - | - | 1 | - | - | - |
Jurado | - | - | 1 | - | - | - |
Pol | - | - | 4 | - | - | - |
Enzo Maresca | - | - | 1 | - | - | - | 530 | 418 | 266 | 112 | 112 | 52 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .