| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Alessandro Florenzi | 36 | 25 | 12 | 11 | 15 | 3 |
Francesco Totti | 34 | 33 | 2 | 1 | 12 | 12 |
Erik Lamela | 33 | 30 | 4 | 3 | 6 | 15 |
Leandro Castan | 30 | 30 | 3 | - | 1 | 1 |
Michael Bradley | 30 | 24 | 8 | 6 | 4 | 1 |
Ivan Piris | 29 | 28 | 8 | 1 | 8 | - |
Dani Osvaldo | 29 | 25 | 8 | 4 | 6 | 16 |
Federico Balzaretti | 27 | 24 | 4 | 3 | 4 | - |
Miralem Pjanic | 27 | 20 | 10 | 7 | 11 | 3 |
Marquinhos | 26 | 22 | 9 | 4 | 1 | - |
Marquinho | 26 | 11 | 22 | 15 | 6 | 4 |
Nicolas Burdisso | 25 | 25 | 8 | - | - | 1 |
Daniele De Rossi | 25 | 21 | 7 | 4 | 4 | - |
Panagiotis Tachtsidis | 21 | 17 | 16 | 4 | 7 | 2 |
Mattia Destro | 21 | 11 | 14 | 10 | 5 | 5 |
Maarten Stekelenburg | 19 | 19 | 7 | - | 1 | - |
Simone Perrotta | 16 | 5 | 26 | 11 | 4 | 2 |
Mauro Goicoechea | 15 | 13 | 16 | 2 | - | - |
Vasilis Torosidis | 11 | 9 | 7 | 2 | 1 | 1 |
Dodo | 11 | 7 | 19 | 4 | 4 | - |
Nicolas Lopez | 6 | - | 30 | 6 | - | 1 |
Bogdan Lobont | 5 | 5 | 23 | - | 1 | - |
Rodrigo Taddei | 4 | 2 | 26 | 2 | - | - |
Alessio Romagnoli | 2 | 1 | 33 | 1 | - | 1 |
Match Forefitted | 1 | 1 | - | - | - | 3 |
Tomas Svedkauskas | - | - | 9 | - | - | - |
Bojan Krkic | - | - | 1 | - | - | - |
Junior Tallo | - | - | 3 | - | - | - |
Jonatan Lucca | - | - | 7 | - | - | - | 509 | 408 | 342 | 101 | 101 | 71 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .