| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Luis Suarez | 5 | 4 | 1 | 1 | 1 | 3 |
Martin Caceres | 4 | 4 | 1 | - | - | - |
Maxi Pereira | 4 | 4 | 1 | - | 1 | - |
Diego Godin | 4 | 4 | 1 | - | - | - |
Diego Lugano | 4 | 4 | 1 | - | - | 1 |
Cristian Rodriguez | 4 | 4 | 1 | - | 2 | - |
Edinson Cavani | 4 | 4 | 1 | - | - | 3 |
Fernando Muslera | 4 | 4 | - | - | - | - |
Walter Gargano | 4 | 3 | 2 | 1 | 1 | - |
Diego Forlan | 4 | 3 | 2 | 1 | - | 1 |
Alvaro Gonzalez | 4 | 2 | 3 | 2 | 1 | - |
Egidio Arevalo | 3 | 3 | 2 | - | 1 | - |
Diego Perez | 3 | 2 | 3 | 1 | 1 | 1 |
Alvaro Pereira | 3 | 1 | 4 | 2 | - | - |
Gaston Ramirez | 2 | 2 | 3 | - | 2 | - |
Sebastian Coates | 2 | 1 | 4 | 1 | - | - |
Nicolas Lodeiro | 2 | 1 | 4 | 1 | - | 1 |
Martin Silva | 1 | 1 | 2 | - | - | - |
Abel Hernandez | 1 | 1 | 4 | - | - | 4 |
Matias Aguirregaray | 1 | 1 | 4 | - | - | - |
Andres Scotti | 1 | 1 | 3 | - | - | - |
Sebastian Eguren | 1 | 1 | 4 | - | - | - |
Juan Castillo | - | - | 4 | - | - | - | 65 | 55 | 55 | 10 | 10 | 14 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .