| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Nigel De Jong | 33 | 32 | 3 | 1 | 5 | 2 |
Kaka | 30 | 27 | 5 | 3 | 11 | 7 |
Mario Balotelli | 30 | 25 | 5 | 5 | 5 | 14 |
Christian Abbiati | 29 | 29 | 2 | - | 1 | - |
Riccardo Montolivo | 29 | 27 | 2 | 2 | 3 | 3 |
Sulley Muntari | 26 | 20 | 9 | 6 | 13 | 5 |
Andrea Poli | 26 | 18 | 16 | 8 | 14 | 2 |
Urby Emanuelson | 23 | 17 | 19 | 6 | 4 | - |
Robinho | 23 | 15 | 16 | 8 | 12 | 3 |
Philippe Mexes | 22 | 22 | 10 | - | - | 2 |
Cristian Zapata | 21 | 20 | 12 | 1 | 1 | 1 |
Kevin Constant | 20 | 19 | 13 | 1 | 6 | - |
Ignazio Abate | 19 | 16 | 10 | 3 | 1 | 1 |
Adil Rami | 18 | 16 | 4 | 2 | - | 3 |
Daniele Bonera | 16 | 15 | 7 | 1 | 2 | - |
Mattia De Sciglio | 16 | 15 | 6 | 1 | 1 | - |
Giampaolo Pazzini | 16 | 7 | 15 | 9 | 1 | 2 |
Valter Birsa | 15 | 10 | 11 | 5 | 9 | 2 |
Alessandro Matri | 15 | 8 | 10 | 7 | 2 | 1 |
Keisuke Honda | 14 | 12 | 5 | 2 | 6 | 1 |
Adel Taarabt | 14 | 12 | 4 | 2 | 3 | 4 |
Cristian Zaccardo | 12 | 7 | 25 | 5 | - | - |
Antonio Nocerino | 11 | 7 | 8 | 4 | 4 | - |
M'Baye Niang | 8 | 1 | 14 | 7 | 1 | - |
Gabriel | 7 | 6 | 24 | 1 | - | - |
Michael Essien | 7 | 3 | 11 | 4 | 1 | - |
Riccardo Saponara | 7 | 2 | 21 | 5 | 2 | - |
Stephan El Shaaraway | 6 | 1 | 7 | 5 | 1 | - |
Matias Silvestre | 4 | 3 | 13 | 1 | - | 1 |
Bryan Cristante | 4 | 3 | 20 | 1 | 1 | 1 |
Marco Amelia | 4 | 3 | 25 | 1 | - | - |
Andrea Petagna | 3 | - | 7 | 3 | - | - |
Luca Lotti | - | - | 1 | - | - | - |
Jherson Vergara | - | - | 6 | - | - | - |
Bakaye Traore | - | - | 1 | - | - | - |
Ferdinando Coppola | - | - | 20 | - | - | - | 528 | 418 | 387 | 110 | 110 | 55 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .