| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Juninho | 34 | 31 | 3 | 3 | 9 | - |
Baggio Husidic | 34 | 26 | 8 | 8 | 15 | 5 |
Gyasi Zardes | 32 | 26 | 7 | 6 | 6 | 16 |
Landon Donovan | 31 | 30 | 1 | 1 | 4 | 10 |
Stefan Ishizaki | 30 | 22 | 9 | 8 | 15 | 5 |
Jaime Penedo | 29 | 29 | 1 | - | - | - |
AJ DeLaGarza | 29 | 28 | 2 | 1 | 3 | - |
Robbie Keane | 29 | 28 | 1 | 1 | 2 | 19 |
Dan Gargan | 29 | 27 | 4 | 2 | 7 | - |
Marcelo Sarvas | 28 | 25 | 3 | 3 | 6 | 3 |
Leonardo | 24 | 20 | 14 | 4 | - | 1 |
Omar Gonzalez | 22 | 22 | - | - | 3 | 4 |
Robbie Rogers | 19 | 15 | 8 | 4 | 3 | - |
Alan Gordon | 14 | 5 | 9 | 9 | 3 | 5 |
Tommy Meyer | 12 | 10 | 18 | 2 | - | - |
Rob Friend | 10 | 4 | 13 | 6 | 3 | - |
Kenney Walker | 8 | 4 | 18 | 4 | 2 | - |
Samuel | 8 | 4 | 9 | 4 | 4 | - |
Chandler Hoffman | 8 | - | 15 | 8 | - | - |
Todd Dunivant | 7 | 5 | 6 | 2 | 3 | - |
Kofi Opare | 6 | 5 | 7 | 1 | - | - |
Jose Villarreal | 5 | - | 8 | 5 | - | - |
James Riley | 4 | 3 | 6 | 1 | 2 | - |
Brian Rowe | 3 | 3 | 27 | - | - | - |
Raul Mendiola | 3 | - | 10 | 3 | - | - |
Brian Perk | 2 | 2 | 7 | - | - | - |
Bradford Jamieson | 2 | - | 7 | 2 | - | - |
Oscar Sorto | 1 | - | 5 | 1 | - | - |
Rafael Garcia | 1 | - | 9 | 1 | - | - |
Charlie Rugg | - | - | 3 | - | - | - | 464 | 374 | 238 | 90 | 90 | 68 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .