| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Danijel Subasic | 37 | 37 | - | - | - | - |
Joao Moutinho | 37 | 35 | 2 | 2 | 1 | 4 |
Fabinho | 36 | 35 | 2 | 1 | 2 | 1 |
Yannick Carrasco | 36 | 33 | 3 | 3 | 16 | 6 |
Anthony Martial | 35 | 19 | 17 | 16 | 18 | 9 |
Bernardo Silva | 31 | 24 | 13 | 7 | 11 | 9 |
Jeremy Toulalan | 28 | 28 | 2 | - | 3 | - |
Valere Germain | 28 | 9 | 28 | 19 | 7 | 4 |
Andrea Raggi | 27 | 27 | 1 | - | 1 | - |
Layvin Kurzawa | 27 | 25 | 4 | 2 | 2 | - |
Nabil Dirar | 27 | 13 | 19 | 14 | 9 | 2 |
Dimitar Berbatov | 26 | 18 | 11 | 8 | 8 | 6 |
Ricardo Carvalho | 24 | 23 | 3 | 1 | 3 | - |
Geoffrey Kondogbia | 24 | 23 | 4 | 1 | 7 | 1 |
Aymen Abdennour | 18 | 17 | 8 | 1 | 1 | - |
Lucas Ocampos | 17 | 7 | 16 | 10 | 7 | 1 |
Wallace | 14 | 11 | 16 | 3 | - | - |
Elderson | 12 | 10 | 18 | 2 | 2 | 1 |
Tiemoue Bakayoko | 12 | 10 | 10 | 2 | 2 | - |
Matheus Carvalho | 9 | 4 | 8 | 5 | 3 | 1 |
Lacina Traore | 6 | 3 | 6 | 3 | 3 | 1 |
Almamy Toure | 5 | 4 | 2 | 1 | 2 | 1 |
Abdou Diallo | 5 | 1 | 13 | 4 | 1 | - |
Radamel Falcao | 3 | 1 | 2 | 2 | 1 | 2 |
Aboubakar Kamara | 2 | - | 3 | 2 | - | - |
Maarten Stekelenburg | 1 | 1 | 36 | - | - | - |
Alain Traore | 1 | - | 6 | 1 | - | - |
Borja Lopez | - | - | 4 | - | - | - |
Abdou Aziz Thiam | - | - | 2 | - | - | - |
Marc-Aurele Caillard | - | - | 2 | - | - | - |
Dylan Bahamboula | - | - | 5 | - | - | - | 528 | 418 | 266 | 110 | 110 | 49 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .