| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Diego Alves | 37 | 37 | 1 | - | 1 | - |
Nicolas Otamendi | 35 | 35 | - | - | 2 | 6 |
Javier Fuego | 35 | 34 | 2 | 1 | 4 | 3 |
Jose Gaya | 35 | 32 | 3 | 3 | 3 | 1 |
Daniel Parejo | 34 | 33 | 1 | 1 | 6 | 11 |
Antonio Barragan | 34 | 32 | 4 | 2 | 3 | 1 |
Shkodran Mustafi | 33 | 33 | 3 | - | 3 | 4 |
Andre Gomes | 33 | 31 | 3 | 2 | 12 | 4 |
Sofiane Feghouli | 33 | 20 | 13 | 13 | 12 | 6 |
Paco Alcacer | 32 | 26 | 6 | 6 | 14 | 11 |
Alvaro Negredo | 30 | 14 | 16 | 16 | 6 | 5 |
Rodrigo Moreno | 29 | 24 | 8 | 5 | 13 | 3 |
Pablo Piatti | 28 | 26 | 4 | 2 | 20 | 7 |
Rodrigo de Paul | 25 | 6 | 27 | 19 | 6 | 1 |
Lucas Orban | 22 | 8 | 27 | 14 | 1 | 1 |
Enzo Perez | 14 | 12 | 4 | 2 | 4 | - |
Joao Cancelo | 10 | 5 | 25 | 5 | - | - |
Carles Gil | 8 | 2 | 12 | 6 | 1 | 1 |
Ruben Vezo | 7 | 6 | 22 | 1 | - | - |
Filipe Augusto | 6 | 1 | 26 | 5 | 1 | - |
Yoel Rodriguez | 4 | 1 | 37 | 3 | - | - |
Roberto Ibanez | 4 | - | 6 | 4 | - | - |
Bruno Zuculini | 1 | - | 9 | 1 | - | - |
Tropi | 1 | - | 3 | 1 | - | - |
Salvador Ruiz | - | - | 3 | - | - | - | 530 | 418 | 265 | 112 | 112 | 65 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .