| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Antoine Griezmann | 37 | 29 | 8 | 8 | 20 | 22 |
Juanfran | 35 | 34 | 3 | 1 | - | - |
Diego Godin | 34 | 34 | 1 | - | - | 3 |
Jorge Koke | 34 | 33 | 1 | 1 | 3 | 2 |
Fernandez Gabi | 34 | 32 | 3 | 2 | 13 | - |
Arda Turan | 32 | 28 | 5 | 4 | 19 | 2 |
Tiago | 31 | 31 | 3 | - | 7 | 5 |
Raul Garcia | 31 | 17 | 15 | 14 | 4 | 5 |
Mario Mandzukic | 28 | 24 | 5 | 4 | 15 | 12 |
Miguel Angel Moya | 27 | 27 | 8 | - | - | - |
Guilherme Siqueira | 26 | 25 | 8 | 1 | 3 | 1 |
Joao Miranda | 24 | 24 | 6 | - | - | 3 |
Saul Niguez | 24 | 9 | 20 | 15 | 5 | 4 |
Mario Suarez | 20 | 11 | 23 | 9 | 3 | 1 |
Raul Jimenez | 20 | 4 | 23 | 16 | 4 | 1 |
Jose Maria Gimenez | 19 | 18 | 19 | 1 | - | 1 |
Fernando Torres | 19 | 10 | 10 | 9 | 9 | 3 |
Jesus Gamez | 14 | 12 | 18 | 2 | 1 | - |
Jan Oblak | 11 | 11 | 27 | - | - | - |
Cristian Ansaldi | 6 | 5 | 12 | 1 | - | - |
Cristian Rodriguez | 6 | - | 9 | 6 | - | - |
Alessio Cerci | 6 | - | 11 | 6 | - | - |
Cani | 4 | - | 13 | 4 | - | - |
Lucas Hernandez | 1 | - | 9 | 1 | - | - |
Hector Hernandez | 1 | - | 2 | 1 | - | - |
Sekou Keita | - | - | 1 | - | - | - |
Bernabe Barragan | - | - | 2 | - | - | - | 524 | 418 | 265 | 106 | 106 | 65 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .