| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Marco Parolo | 34 | 34 | - | - | 3 | 10 |
Antonio Candreva | 34 | 31 | 3 | 3 | 10 | 10 |
Miroslav Klose | 34 | 21 | 16 | 13 | 15 | 13 |
Felipe Anderson | 32 | 23 | 12 | 9 | 8 | 10 |
Federico Marchetti | 30 | 30 | 1 | - | - | - |
Stefan de Vrij | 30 | 29 | 1 | 1 | 3 | - |
Stefano Mauri | 29 | 25 | 7 | 4 | 19 | 9 |
Dusan Basta | 27 | 27 | 1 | - | 2 | - |
Lucas Biglia | 27 | 27 | - | - | 5 | 3 |
Senad Lulic | 25 | 22 | 5 | 3 | 9 | 3 |
Stefan Radu | 24 | 24 | 1 | - | 3 | - |
Filip Dordevic | 24 | 15 | 11 | 9 | 10 | 8 |
Keita Balde | 23 | 6 | 27 | 17 | 5 | 1 |
Lorik Cana | 17 | 15 | 12 | 2 | 1 | - |
Edson Braafheid | 16 | 12 | 18 | 4 | 5 | - |
Danilo Cataldi | 16 | 11 | 15 | 5 | 3 | - |
Luis Pedro Cavanda | 16 | 10 | 20 | 6 | 1 | - |
Ogenyi Onazi | 16 | 6 | 30 | 10 | 3 | 1 |
Mauricio | 15 | 14 | 3 | 1 | 1 | - |
Cristian Ledesma | 13 | 7 | 31 | 6 | 4 | - |
Michael Ciani | 12 | 9 | 9 | 3 | 1 | - |
Etrit Berisha | 10 | 8 | 27 | 2 | - | - |
Santiago Gentiletti | 5 | 5 | 3 | - | 2 | 1 |
Diego Novaretti | 5 | 2 | 30 | 3 | - | - |
Brayan Perea | 5 | - | 17 | 5 | - | - |
Alvaro Gonzalez | 4 | 2 | 10 | 2 | - | - |
Honorato Ederson | 4 | - | 19 | 4 | - | 1 |
Bruno Pereirinha | 3 | 2 | 18 | 1 | 1 | - |
Abdoulay Konko | 2 | 1 | 23 | 1 | - | - |
Mamadou Tounkara | - | - | 4 | - | - | - |
Guido Guerrieri | - | - | 7 | - | - | - |
Thomas Strakosha | - | - | 36 | - | - | - |
Christopher Ikonomidis | - | - | 3 | - | - | - | 532 | 418 | 420 | 114 | 114 | 70 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .