| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Morgan De Sanctis | 35 | 35 | 1 | - | - | - |
Radja Nainggolan | 35 | 30 | 6 | 5 | 3 | 5 |
Alessandro Florenzi | 35 | 24 | 11 | 11 | 8 | 5 |
Miralem Pjanic | 34 | 28 | 6 | 6 | 12 | 5 |
Adem Ljajic | 32 | 23 | 14 | 9 | 16 | 8 |
Kostas Manolas | 30 | 30 | 3 | - | 2 | - |
Mapou Yanga-Mbiwa | 28 | 22 | 13 | 6 | - | 1 |
Francesco Totti | 27 | 24 | 10 | 3 | 20 | 8 |
Juan Iturbe | 27 | 17 | 14 | 10 | 13 | 2 |
Daniele De Rossi | 26 | 25 | 4 | 1 | 6 | 2 |
Seydou Keita | 26 | 18 | 9 | 8 | 2 | 2 |
Jose Holebas | 24 | 23 | 11 | 1 | 1 | 1 |
Davide Astori | 24 | 22 | 7 | 2 | 1 | 1 |
Gervinho | 24 | 21 | 6 | 3 | 3 | 2 |
Vasilis Torosidis | 20 | 17 | 14 | 3 | 5 | 2 |
Mattia Destro | 16 | 8 | 12 | 8 | 1 | 5 |
Maicon | 14 | 11 | 6 | 3 | 3 | 1 |
Seydou Doumbia | 13 | 6 | 9 | 7 | 4 | 2 |
Ashley Cole | 11 | 11 | 27 | - | - | - |
Victor Ibarbo | 10 | 6 | 5 | 4 | 3 | - |
Leandro Paredes | 10 | 4 | 28 | 6 | 4 | 1 |
Daniele Verde | 7 | 1 | 19 | 6 | - | - |
Kevin Strootman | 5 | 4 | 5 | 1 | 2 | - |
Salih Ucan | 4 | 2 | 25 | 2 | 1 | - |
Lukasz Skorupski | 3 | 3 | 32 | - | - | - |
Antonio Sanabria | 2 | - | 22 | 2 | - | - |
Urby Emanuelson | 2 | - | 19 | 2 | - | - |
Leandro Castan | 1 | 1 | - | - | 1 | - |
Nicolas Spolli | 1 | 1 | 12 | - | - | - |
Federico Balzaretti | 1 | 1 | 9 | - | - | - |
Michele Somma | 1 | - | 19 | 1 | - | - |
Lorenzo Pellegrini | 1 | - | 12 | 1 | - | - |
Gianluca Curci | - | - | 3 | - | - | - |
Arturo Calabresi | - | - | 6 | - | - | - |
Tomas Vestenicky | - | - | 3 | - | - | - |
Marco Borriello | - | - | 11 | - | - | - |
Alessio Romagnoli | - | - | 1 | - | - | - |
Bogdan Lobont | - | - | 18 | - | - | - |
Gabriele Marchegiani | - | - | 2 | - | - | - | 529 | 418 | 434 | 111 | 111 | 53 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .