| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Wout Weghorst | 34 | 33 | 1 | 1 | 7 | 17 |
Maximilian Arnold | 33 | 33 | - | - | 7 | 2 |
Robin Knoche | 31 | 31 | 3 | - | - | 3 |
William | 31 | 30 | 1 | 1 | 2 | 2 |
Renato Steffen | 31 | 18 | 15 | 13 | 15 | 5 |
Yannick Gerhardt | 30 | 28 | 4 | 2 | 7 | 2 |
John Anthony Brooks | 29 | 29 | - | - | - | 3 |
Jerome Roussillon | 28 | 28 | - | - | 5 | 3 |
Koen Casteels | 26 | 26 | - | - | 1 | - |
Admir Mehmedi | 26 | 20 | 7 | 6 | 13 | 6 |
Josip Brekalo | 25 | 15 | 17 | 10 | 9 | 3 |
Elvis Rexhbecaj | 24 | 13 | 19 | 11 | 11 | 2 |
Daniel Ginczek | 24 | 12 | 12 | 12 | 7 | 6 |
Yunis Malli | 21 | 5 | 28 | 16 | 3 | 1 |
Josuha Guilavogui | 19 | 18 | 1 | 1 | 2 | 2 |
Felix Klaus | 15 | 5 | 14 | 10 | 5 | 1 |
Ohis Felix Uduokhai | 11 | 2 | 29 | 9 | - | - |
Marcel Tisserand | 10 | 10 | 3 | - | 2 | 1 |
Pavao Pervan | 9 | 8 | 26 | 1 | - | - |
Ignacio Camacho | 6 | 6 | - | - | - | - |
Paul Verhaegh | 2 | 2 | 26 | - | - | - |
Luca Itter | 2 | 1 | 5 | 1 | - | - |
John Yeboah Zamora | 2 | - | 7 | 2 | - | - |
Sebastian Jung | 1 | 1 | 4 | - | 1 | - |
Jakub Blaszczykowski | 1 | - | 2 | 1 | - | - |
Phillip Menzel | - | - | 8 | - | - | - |
Dominik Franke | - | - | 3 | - | - | - |
Jeffrey Bruma | - | - | 1 | - | - | - |
Robin Ziegele | - | - | 1 | - | - | - | 471 | 374 | 237 | 97 | 97 | 59 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .