| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Maximilian Arnold | 33 | 32 | 1 | 1 | 6 | 4 |
Wout Weghorst | 32 | 30 | 2 | 2 | 3 | 16 |
Joao Victor | 32 | 18 | 16 | 14 | 14 | 2 |
Josip Brekalo | 30 | 19 | 15 | 11 | 16 | 3 |
Jerome Roussillon | 29 | 27 | 4 | 2 | 6 | 1 |
Renato Steffen | 27 | 19 | 13 | 8 | 12 | 6 |
Koen Casteels | 26 | 26 | - | - | - | - |
John Anthony Brooks | 25 | 25 | 5 | - | 2 | - |
Josuha Guilavogui | 25 | 23 | 3 | 2 | 2 | - |
Xaver Schlager | 23 | 21 | 4 | 2 | 8 | 1 |
Felix Klaus | 23 | 6 | 25 | 17 | 6 | - |
Robin Knoche | 21 | 17 | 17 | 4 | 2 | 1 |
Admir Mehmedi | 21 | 14 | 7 | 7 | 12 | 2 |
Kevin Mbabu | 20 | 18 | 15 | 2 | - | 3 |
Daniel Ginczek | 18 | 9 | 12 | 9 | 9 | 3 |
Yannick Gerhardt | 18 | 7 | 23 | 11 | 2 | 2 |
William | 16 | 16 | 5 | - | 2 | 1 |
Marcel Tisserand | 15 | 14 | 15 | 1 | 1 | 1 |
Marin Pongracic | 11 | 11 | 1 | - | 1 | 2 |
Jeffrey Bruma | 9 | 9 | 6 | - | - | - |
Pavao Pervan | 8 | 8 | 26 | - | - | - |
Lukas Nmecha | 6 | 1 | 11 | 5 | 1 | - |
Paulo Otavio | 5 | 4 | 8 | 1 | 1 | - |
Omar Marmoush | 5 | - | 9 | 5 | - | - |
Mamoudou Karamoko | 1 | - | 2 | 1 | - | - |
Luca Horn | 1 | - | 6 | 1 | - | - |
Elvis Rexhbecaj | - | - | 12 | - | - | - |
Lino Kasten | - | - | 1 | - | - | - |
Ohis Felix Uduokhai | - | - | 1 | - | - | - |
Phillip Menzel | - | - | 8 | - | - | - |
Iba May | - | - | 6 | - | - | - |
Julian Justvan | - | - | 9 | - | - | - |
Yunis Malli | - | - | 9 | - | - | - |
Niklas Klinger | - | - | 1 | - | - | - |
Ismail Azzaoui | - | - | 5 | - | - | - |
Ulysses Llanez | - | - | 2 | - | - | - | 480 | 374 | 305 | 106 | 106 | 48 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .