| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Edin Dzeko | 35 | 31 | 7 | 4 | 4 | 16 |
Jordan Veretout | 33 | 30 | 6 | 3 | 7 | 6 |
Pau Lopez | 32 | 32 | 2 | - | - | - |
Gianluca Mancini | 32 | 31 | 2 | 1 | 3 | 1 |
Aleksandar Kolarov | 32 | 30 | 7 | 2 | - | 7 |
Chris Smalling | 30 | 29 | 2 | 1 | 1 | 3 |
Lorenzo Pellegrini | 27 | 26 | 1 | 1 | 13 | 2 |
Bryan Cristante | 26 | 18 | 8 | 8 | 4 | 1 |
Nicolo Zaniolo | 26 | 16 | 10 | 10 | 10 | 6 |
Leonardo Spinazzola | 24 | 18 | 15 | 6 | 6 | 1 |
Amadou Diawara | 22 | 19 | 9 | 3 | 8 | 1 |
Henrikh Mkhitaryan | 22 | 16 | 8 | 6 | 10 | 9 |
Justin Kluivert | 21 | 18 | 13 | 3 | 11 | 4 |
Diego Perotti | 21 | 10 | 18 | 11 | 8 | 5 |
Cengiz Under | 18 | 10 | 19 | 8 | 8 | 3 |
Bruno Peres | 17 | 12 | 7 | 5 | 6 | 2 |
Federico Fazio | 16 | 14 | 15 | 2 | 3 | 1 |
Davide Santon | 15 | 7 | 18 | 8 | 5 | - |
Nikola Kalinic | 15 | 6 | 24 | 9 | 3 | 5 |
Alessandro Florenzi | 14 | 12 | 7 | 2 | 7 | - |
Carles Perez | 13 | 5 | 12 | 8 | 4 | 1 |
Javier Pastore | 11 | 5 | 21 | 6 | 4 | - |
Davide Zappacosta | 10 | 4 | 10 | 6 | - | - |
Roger Ibanez | 9 | 7 | 7 | 2 | 3 | - |
Gonzalo Villar | 9 | 2 | 15 | 7 | - | - |
Mert Cetin | 6 | 2 | 25 | 4 | - | - |
Antonio Mirante | 5 | 5 | 20 | - | - | - |
Juan | 4 | 1 | 22 | 3 | 1 | - |
Mirko Antonucci | 2 | - | 18 | 2 | 1 | - |
Riccardo Calafiori | 1 | 1 | 3 | - | 1 | - |
Daniel Fuzato | 1 | 1 | 34 | - | - | - |
Patrik Schick | - | - | 2 | - | - | - |
Alessio Riccardi | - | - | 1 | - | - | - |
Matteo Cardinali | - | - | 2 | - | - | - |
Emanuele Spinozzi | - | - | 1 | - | - | - | 549 | 418 | 391 | 131 | 131 | 74 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .