| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Daniel Parejo | 36 | 36 | - | - | 8 | 3 |
Sergio Asenjo | 36 | 36 | 2 | - | - | - |
Raul Albiol | 35 | 35 | 2 | - | 4 | - |
Manu Trigueros | 35 | 30 | 6 | 5 | 17 | 1 |
Moises Gomez | 35 | 29 | 6 | 6 | 15 | 4 |
Gerard Moreno | 34 | 30 | 3 | 4 | 11 | 23 |
Pau Torres | 33 | 33 | 3 | - | - | 2 |
Alfonso Pedraza | 29 | 24 | 10 | 5 | 12 | 1 |
Samuel Chukwueze | 28 | 13 | 16 | 15 | 10 | 4 |
Paco Alcacer | 27 | 19 | 10 | 8 | 19 | 6 |
Pervis Estupinan | 25 | 12 | 18 | 13 | 5 | - |
Mario Gaspar | 24 | 21 | 5 | 3 | 4 | - |
Yeremi Pino | 24 | 6 | 23 | 18 | 5 | 3 |
Carlos Bacca | 23 | 9 | 23 | 14 | 9 | 5 |
Francis Coquelin | 22 | 7 | 17 | 15 | 8 | - |
Ruben Pena | 19 | 12 | 14 | 7 | 3 | 1 |
Fernando Nino | 17 | 8 | 28 | 9 | 8 | 3 |
Etienne Capoue | 16 | 15 | 3 | 1 | 10 | 1 |
Juan Foyth | 16 | 13 | 10 | 3 | 4 | - |
Jaume Costa | 14 | 3 | 33 | 11 | 3 | - |
Vicente Iborra | 13 | 10 | 3 | 3 | 2 | - |
Takefusa Kubo | 13 | 2 | 14 | 11 | 2 | - |
Ramiro Funes Mori | 9 | 8 | 28 | 1 | 2 | - |
Alex Baena | 6 | 2 | 36 | 4 | 2 | - |
Alberto Moreno | 5 | 2 | 9 | 3 | 2 | - |
Daniel Raba | 5 | 1 | 22 | 4 | - | - |
Geronimo Rulli | 2 | 2 | 33 | - | - | - |
Alejandro Millan | 1 | - | 2 | 1 | - | - |
Sofian Chakla | 1 | - | 9 | 1 | - | - |
Andrei Ratiu | - | - | 4 | - | - | - |
Javi Ontiveros | - | - | 2 | - | - | - |
Filip Jorgensen | - | - | 2 | - | - | - |
Lanchi | - | - | 3 | - | - | - |
Sergio Lozano | - | - | 1 | - | - | - |
Carlo Garcia | - | - | 1 | - | - | - |
Iker Alvarez | - | - | 3 | - | - | - |
Cristian Espinoza | - | - | 1 | - | - | - | 583 | 418 | 405 | 165 | 165 | 57 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .