| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Lautaro Martinez | 38 | 30 | 8 | 8 | 23 | 17 |
Samir Handanovic | 37 | 37 | 1 | - | 2 | - |
Achraf Hakimi | 37 | 29 | 8 | 8 | 11 | 7 |
Nicolo Barella | 36 | 32 | 5 | 4 | 9 | 3 |
Romelu Lukaku | 36 | 32 | 5 | 4 | 7 | 24 |
Alessandro Bastoni | 33 | 33 | 3 | - | 4 | - |
Marcelo Brozovic | 33 | 29 | 5 | 4 | 8 | 2 |
Milan Skriniar | 32 | 31 | 4 | 1 | 3 | 3 |
Stefan de Vrij | 32 | 30 | 7 | 2 | - | 1 |
Ivan Perisic | 32 | 20 | 16 | 12 | 15 | 4 |
Alexis Sanchez | 30 | 12 | 20 | 18 | 10 | 7 |
Roberto Gagliardini | 28 | 14 | 22 | 14 | 10 | 3 |
Christian Eriksen | 26 | 17 | 20 | 9 | 15 | 3 |
Ashley Young | 26 | 16 | 20 | 10 | 12 | 1 |
Matteo Darmian | 26 | 14 | 20 | 12 | 12 | 3 |
Arturo Vidal | 23 | 14 | 12 | 9 | 12 | 1 |
Danilo D'Ambrosio | 19 | 7 | 26 | 12 | 1 | 3 |
Stefano Sensi | 18 | 4 | 27 | 14 | 4 | - |
Andrea Ranocchia | 8 | 8 | 29 | - | 1 | - |
Matias Vecino | 8 | 3 | 14 | 5 | 1 | 1 |
Andrea Pinamonti | 8 | 1 | 27 | 7 | 1 | 1 |
Aleksandar Kolarov | 7 | 4 | 19 | 3 | - | - |
Radja Nainggolan | 4 | - | 5 | 4 | - | - |
Ionut Radu | 2 | 1 | 34 | 1 | - | - |
Daniele Padelli | 1 | - | 33 | 1 | - | - |
Niccolo Squizzato | - | - | 1 | - | - | - |
Franco Vezzoni | - | - | 3 | - | - | - |
Franco Carboni | - | - | 2 | - | - | - |
Lorenzo Pirola | - | - | 2 | - | - | - |
Dalbert | - | - | 2 | - | - | - |
Martin Satriano | - | - | 3 | - | - | - |
Lorenzo Moretti | - | - | 5 | - | - | - |
David Wieser | - | - | 1 | - | - | - |
Filip Stankovic | - | - | 5 | - | - | - |
Bruno Peres | - | - | - | - | 1 | - | 580 | 418 | 414 | 162 | 162 | 84 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .