| Players | Total | Start | Sub | CO | Off | Goals |
|---|---|---|---|---|---|---|
 Duvan Zapata | 37 | 29 | 8 | 8 | 26 | 15 |
Jose Luis Palomino | 36 | 25 | 12 | 11 | 2 | 1 |
Ruslan Malinovskiy | 36 | 22 | 14 | 14 | 19 | 8 |
Luis Muriel | 36 | 16 | 21 | 20 | 16 | 22 |
Marten de Roon | 35 | 33 | 2 | 2 | 1 | 1 |
Remo Freuler | 34 | 32 | 6 | 2 | 11 | 2 |
Berat Djimsiti | 33 | 28 | 7 | 5 | 5 | - |
Robin Gosens | 32 | 30 | 2 | 2 | 17 | 10 |
Cristian Romero | 31 | 29 | 5 | 2 | 5 | 2 |
Rafael Toloi | 31 | 29 | 3 | 2 | 6 | 2 |
Matteo Pessina | 28 | 21 | 12 | 7 | 16 | 2 |
Josip Ilicic | 28 | 17 | 16 | 11 | 15 | 6 |
Pierluigi Gollini | 25 | 25 | 7 | - | 1 | - |
Mario Pasalic | 25 | 10 | 17 | 15 | 5 | 6 |
Aleksei Miranchuk | 25 | 4 | 29 | 21 | 4 | 4 |
Hans Hateboer | 21 | 20 | 3 | 1 | 5 | 2 |
Joakim Maehle | 20 | 12 | 11 | 8 | 3 | - |
Marco Sportiello | 15 | 13 | 25 | 2 | - | - |
Sam Lammers | 15 | 1 | 35 | 14 | 1 | 2 |
Johan Mojica | 11 | 3 | 11 | 8 | 2 | - |
Papu Gomez | 10 | 9 | 2 | 1 | 7 | 4 |
Bosko Sutalo | 7 | 3 | 28 | 4 | 2 | - |
Matteo Ruggeri | 6 | 3 | 27 | 3 | 3 | - |
Mattia Caldara | 6 | 1 | 26 | 5 | 1 | - |
Fabio Depaoli | 5 | 3 | 14 | 2 | 1 | - |
Emmanuel Gyabuaa | 1 | - | 4 | 1 | - | - |
Viktor Kovalenko | 1 | - | 14 | 1 | - | - |
Davide Ghislandi | 1 | - | 6 | 1 | - | - |
Cristiano Piccini | 1 | - | 3 | 1 | 1 | - |
Amad Diallo | 1 | - | 10 | 1 | - | - |
Boris Radunovic | - | - | 2 | - | - | - |
Jacopo Da Riva | - | - | 1 | - | - | - |
Giorgio Scalvini | - | - | 2 | - | - | - |
Francesco Rossi | - | - | 38 | - | - | - |
Simone Panada | - | - | 1 | - | - | - |
Marco Carnesecchi | - | - | 3 | - | - | - |
Ludovico Gelmi | - | - | 1 | - | - | - | 593 | 418 | 428 | 175 | 175 | 89 |
Total = Total appearances,
Start = Total started,
CO = Came on,
Sub = Started as a sub,
Off = Taken off .