| # | Players | Clubs | Nationality | GC | More |
|---|---|---|---|---|---|
| 1 | Stefano Sorrentino | Recreativo | Italy | 61 | |
| 2 | Cesar Sanchez | Real Zaragoza | Spain | 59 | |
| 3 | Carlos Kameni | Espanyol | Cameroon | 44 | |
| 4 | Ricardo | Osasuna | Spain | 43 | |
| 5 | Ricardo | Real Betis | Portugal | 43 | |
| 6 | Roberto Abbondanzieri | Getafe | Argentina | 42 | |
| 7 | Andres Palop | Sevilla | Spain | 42 | |
| 8 | Antonio Notario | Real Murcia | Spain | 41 | |
| 9 | Timo Hildebrand | Valencia | Germany | 40 | |
| 10 | Miguel Angel Moya | RCD Mallorca | Spain | 36 | |
| 11 | Victor Valdes | Barcelona | Spain | 35 | |
| 12 | Iker Casillas | Real Madrid | Spain | 33 | |
| 13 | Marco Storari | Levante | Italy | 33 | |
| 14 | Dudu Aouate | Deportivo La Coruna | Israel | 32 | |
| 15 | Tono | Racing Santander | Spain | 30 | |
| 16 | Sergio Asenjo | Real Valladolid | Spain | 28 | |
| 17 | Christian Abbiati | Atletico Madrid | Italy | 28 | |
| 18 | Sebastian Viera | Villarreal | Uruguay | 25 | |
| 19 | Vladan Kujovic | Levante | Croatia | 24 | |
| 20 | Diego Alves | UD Almeria | Brazil | 23 |
GC = Goals conceded