| # | Players | Clubs | Nationality | GC | More |
|---|---|---|---|---|---|
| 1 | Orestis Karnezis | Udinese | Greece | 61 | |
| 2 | Nicola Leali | Frosinone | Italy | 60 | |
| 3 | Stefano Sorrentino | Palermo | Italy | 60 | |
| 4 | Emiliano Viviano | Sampdoria | Italy | 59 | |
| 5 | Daniele Padelli | Torino | Italy | 52 | |
| 6 | Marco Sportiello | Atalanta | Italy | 47 | |
| 7 | Vid Belec | Carpi | Slovenia | 44 | |
| 8 | Lukasz Skorupski | Empoli | Poland | 44 | |
| 9 | Albano Bizzarri | Chievo | Argentina | 43 | |
| 10 | Ciprian Tatarusanu | Fiorentina | Romania | 42 | |
| 11 | Pierluigi Gollini | Hellas Verona | Italy | 41 | |
| 12 | Antonio Mirante | Bologna | Italy | 41 | |
| 13 | Andrea Consigli | Sassuolo | Italy | 40 | |
| 14 | Federico Marchetti | SS Lazio | Italy | 40 | |
| 15 | Samir Handanovic | Internazionale | Slovenia | 35 | |
| 16 | Wojciech Szczesny | AS Roma | Poland | 34 | |
| 17 | Mattia Perin | Genoa | Italy | 31 | |
| 18 | Pepe Reina | Napoli | Spain | 31 | |
| 19 | Gianluigi Donnarumma | AC Milan | Italy | 29 | |
| 20 | Gianluigi Buffon | Juventus | Italy | 20 |
GC = Goals conceded